ArticleSurgery today2018
The impact of the Charlson comorbidity index on the prognosis of esophageal cancer patients who underwent esophagectomy with curative intent.
Article in Surgery today, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 44 citations in OpenAlex.
- The geriatric 8 score as a predictor of postoperative outcomes in elderly patients undergoing esophagectomy.General thoracic and cardiovascular surgery · 2026Article
- Associations between comorbidities and survival outcomes in older adults with cancer: a scoping review of international and Japanese evidence.BMC geriatrics · 2026Article
- Preoperative exercise capacity as a predictor of postoperative pulmonary complications in patients with esophageal cancer: a multicenter observational cohort study.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- A full-cycle integrated management model for esophageal cancer in county health systems: effects on care processes, clinical outcomes, quality of life, and cost-utility.Frontiers in oncology · 2026Article
- Factors responsible for the decline in physical fitness during neoadjuvant chemotherapy in older patients with esophageal cancer: an exploratory prospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Association between accelerometer-measured light-intensity physical activity and tumor regression for male patients with esophageal cancer receiving neoadjuvant therapy: a retrospective cohort study.Esophagus : official journal of the Japan Esophageal Society · 2025Observational
- Proposal of "borderline resectable" colorectal liver metastases based on analysis of risk factors for early surgical failure.Surgery today · 2025Article
- High comprehensive complication index after minimally invasive esophagectomy associated with poor short-term and long-term outcome: a propensity score matching analysis.Frontiers in oncology · 2025Article
- Prognosis of radiotherapy for esophageal cancer in elderly patients exceeding seventy-five years old.World journal of gastrointestinal oncology · 2024Article
- Indications for neoadjuvant chemotherapy in older patients undergoing esophagectomy for esophageal cancer.Surgery today · 2024Article
- Clinical Impact of the Charlson Comorbidity Index on the Efficacy of Salvage Photodynamic Therapy Using Talaporfin Sodium for Esophageal Cancer.Internal medicine (Tokyo, Japan) · 2024Article
- Survival Impacts of Impaired Lung Functions and Comorbidities on Elderly Esophageal Cancer Patients.World journal of surgery · 2023Article
- The impact of postoperative blood glucose levels on complications and prognosis after esophagectomy in patients with esophageal cancer.Surgery today · 2023Article
- Ejection fraction at hospital admission stratifies mortality risk in HFmrEF patients aged ≥ 70 years: a retrospective analysis from a tertiary university institution.Aging clinical and experimental research · 2023Article
- Postoperative respiratory morbidity can adversely affect prognosis in thoracoscopic esophagectomy for esophageal cancer: a retrospective study.Surgical endoscopy · 2023Article
- Prognostic Impact of the Loss of Skeletal Muscle Mass During Neoadjuvant Chemotherapy on Older Patients with Esophageal Cancer.Annals of surgical oncology · 2022Article
- Short- (30-90 days) and mid-term (1-3 years) outcomes and prognostic factors of patients with esophageal cancer undergoing surgical treatments.World journal of clinical cases · 2022Article
- Effect of sex on survival after resection of oesophageal cancer: nationwide cohort study.BJS open · 2022Article
- Efficacy of neoadjuvant chemotherapy in patients with high-risk resectable colorectal liver metastases.International journal of clinical oncology · 2021Article
- Long-term Outcomes and Factors Affecting the Survival of Patients with Mucosal Esophageal Squamous Cell Carcinoma.Gut and liver · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to clarify the influence of Charlson comorbidity index (CCI) on treatment options, and on short- and mid-term outcomes in esophageal cancer patients who underwent esophagectomy.
methodsPatients who underwent curative-intent esophagectomy from 2009 to 2014 were classified by CCI. A CCI of ≥ 2 was defined as high, while a CCI of 0 or 1 was classified as low. Clinicopathological parameters, including overall survival (OS) and disease-specific survival (DSS), were compared between the groups.
resultsAmong 548 patients, the most frequent comorbidity was chronic obstructive pulmonary disease (n = 142, 25.9%), followed by solid tumor (n = 79, 14.4%). A high CCI was significantly correlated with older age (P < 0.001), surgery alone (P = 0.020), a lower number of dissected lymph nodes (P < 0.001), lower rate of R0 resection (P = 0.048), and prolonged hospital stay (P < 0.001). In the low group, OS after surgery was favorable in comparison to the the high group. Although DSS was comparable between the groups, the CCI was significantly associated with a poor prognosis in patients with stage ≥ II disease.
conclusionsThe CCI was significantly correlated with the prognosis of esophageal cancer patients who underwent curative-intent esophagectomy.
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