Evidence map›Paper›PMID 29383521›Full record

ArticleEuropean radiology2018

Standard diffusion-weighted, diffusion kurtosis and intravoxel incoherent motion MR imaging of sinonasal malignancies: correlations with Ki-67 proliferation status.

Zebin Xiao, Yufeng Zhong, Zuohua Tang, Jinwei Qiang, Wen Qian, Rong Wang, Jie Wang, Lingjie Wu, Wenlin Tang, Zhongshuai Zhang

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Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

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40citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zebin XiaoDepartment of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.
Yufeng ZhongDepartment of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.
Zuohua TangDepartment of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China. tzh518sunny@163.com.
Jinwei QiangDepartment of Radiology, Jinshan Hospital of Shanghai Medical School, Fudan University, 1508 Longhang Road, Shanghai, 201508, People's Republic of China. dr.jinweiqiang@163.com.
Wen QianDepartment of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.
Rong WangDepartment of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.
Jie WangDepartment of Radiotherapy, Eye & ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, 200031, China.
Lingjie WuDepartment of Otolaryngology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, 200031, China.
Wenlin TangSiemens Healthcare Ltd., Shanghai, 201318, People's Republic of China.
Zhongshuai ZhangSiemens Healthcare Ltd., Shanghai, 201318, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the correlations of parameters derived from standard diffusion-weighted imaging (DWI), diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) with the Ki-67 proliferation status.

methodsSeventy-five patients with histologically proven sinonasal malignancies who underwent standard DWI, DKI and IVIM were retrospectively reviewed. The mean, minimum, maximum and whole standard DWI [apparent diffusion coefficient (ADC)], DKI [diffusion kurtosis (K) and diffusion coefficient (Dk)] and IVIM [pure diffusion coefficient (D), pseudo-diffusion coefficient (D*) and perfusion fraction (f)] parameters were measured and correlated with the Ki-67 labelling index (LI). The Ki-67 LI was categorised as high (> 50%) or low (≤ 50%).

resultsThe K and f values were positively correlated with the Ki-67 LI (rho = 0.295~0.532), whereas the ADC, Dk and D values were negatively correlated with the Ki-67 LI (rho = -0.443~-0.277). The ADC, Dk and D values were lower, whereas the K value was higher in sinonasal malignancies with a high Ki-67 LI than in those in a low Ki-67 LI (all p < 0.05). A higher maximum K value (K

conclusionADC, Dk, K, D and f are correlated with Ki-67 LI. K KEY POINTS: • DWI-derived parameters from different models are capable of providing different pathophysiological information. • DWI, DKI and IVIM parameters are associated with Ki-67 proliferation status. • K

Indexed as

Cell ProliferationAdultAgedAged, 80 and overDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFemaleHumansKi-67 AntigenMagnetic Resonance ImagingMaleMiddle AgedNasal CavityNose NeoplasmsParanasal SinusesRetrospective StudiesKi-67 AntigenDiffusion magnetic resonance imagingImmunohistochemistryMagnetic resonance imagingNeoplasmsPrognosis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.