Evidence map›Paper›PMID 29383493›Full record

ArticleNeurology and therapy2018

Treatment with Botulinum Toxin for Refractory Fever Caused by Severe Spasticity: A Case Series.

Jacobo Lester, Gerardo Esteban Alvarez-Resendiz, Enrique Klériga, Fernando Videgaray, Gerardo Zambito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Efficacy and Safety of Botulinum Toxin Type A in Spasticity Caused by Spinal Cord Injury: A Randomized, Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jacobo LesterNeurology/Movement Disorders, Instituto Mexicano de Neurociencias, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico. jacobolester@hotmail.com.
Gerardo Esteban Alvarez-ResendizAnesthesiology, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.
Enrique KlérigaNeurosurgery, Instituto Mexicano de Neurociencias, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.
Fernando VidegarayInternal Medicine/Infectology, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.
Gerardo ZambitoNeurosurgery, Instituto Mexicano de Neurociencias, Hospital Angeles Lomas, Huixquilucan, Estado de México, Mexico.
Instituto de Salud del Estado de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBrain and spinal cord injuries may cause very severe spasticity that occasionally may be associated with persistent fever. CASE SERIES: We present 14 patients with spasticity and persistent fever, treated with botulinum toxin type A. Their spasticity improved and the fever resolved within a period no greater than 48 h. In all cases, infectious and other non-infectious causes were ruled out.

conclusionsWhen sustained tonic muscular activity is associated with a significant increase in body temperature and is refractory to the usual drugs used for hyperpyrexia, type A botulinum toxin may be an effective treatment option to control both spasticity and fever.

Indexed as

Botulinum toxinFeverSpasticity

Identifiers

PMID29383493
PMCPMC5990504
OpenAlexW2791643175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.