Evidence map›Paper›PMID 29382969›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2018

Comparison of the oral and rectal mucosal and colonic serosal microcirculations of healthy, anesthetized horses.

Philip J Kieffer, Jarred M Williams, Molly K Shepard, Steeve Giguère, Kira L Epstein

Abstract readComparative Study
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philip J KiefferDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA (Kieffer, Williams, Giguère, Epstein); MedVet Medical & Cancer Centers for Pets, Chicago, Illinois, USA (Shepard).
Jarred M WilliamsDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA (Kieffer, Williams, Giguère, Epstein); MedVet Medical & Cancer Centers for Pets, Chicago, Illinois, USA (Shepard).
Molly K ShepardDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA (Kieffer, Williams, Giguère, Epstein); MedVet Medical & Cancer Centers for Pets, Chicago, Illinois, USA (Shepard).
Steeve GiguèreDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA (Kieffer, Williams, Giguère, Epstein); MedVet Medical & Cancer Centers for Pets, Chicago, Illinois, USA (Shepard).
Kira L EpsteinDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA (Kieffer, Williams, Giguère, Epstein); MedVet Medical & Cancer Centers for Pets, Chicago, Illinois, USA (Shepard).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objectives of the study were to: i) determine baseline microvascular perfusion indices (MPI) and assess their repeatability in healthy horses under general anesthesia, and ii) compare the MPIs of 3 microvascular beds (oral mucosa, colonic serosa, and rectal mucosa). Healthy adult horses were anesthetized and sidestream dark field microscopy was used to collect video loops of the oral mucosa, rectal mucosa, and colonic serosa under normotensive conditions without cardiovascular support drugs; videos were later analyzed to produce MPIs. Baseline MPI values were determined for each site, which included the total vessel density (TVD), perfused vessel density (PVD), portion perfused vessels (PPV), and microcirculatory flow index (MFI). Differences in MPIs between microvascular beds were not statistically significant. Repeatability of the measurements varied for each MPI. In particular, the site of sampling had a profound effect on the repeatability of the PPV measurements and should be considered in future studies.

Indexed as

MicrocirculationAnesthesia, GeneralAnimalsBlood PressureColonFemaleHorsesIntestinal MucosaMaleMouth MucosaRectumVideo Recording

Identifiers

PMID29382969
PMCPMC5764044

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.