Evidence map›Paper›PMID 29382785›Full record

ArticleScience signaling2018

Fluorescent Ca

Nathan A Smith, Benjamin T Kress, Yuan Lu, Devin Chandler-Militello, Abdellatif Benraiss, Maiken Nedergaard

Open access · bronzeAbstract read
In one paragraph

Article in Science signaling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Guideline
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  7. Review
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  10. Review
  11. Article
  12. Article
  13. Saturated fatty acids stimulate cytokine production in tanycytes via the PP2Ac-dependent signaling pathway.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  14. Article
  15. Amyloid plaques and normal ageing have differential effects on microglial CaPflugers Archiv : European journal of physiology · 2024
    Article
  16. Article
  17. Article
  18. A Dynamic Balance between Neuronal Death and Clearance in anThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  19. Comparing the effects of chemical CaJournal of molecular and cellular cardiology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nathan A SmithCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-9254-5360
Benjamin T KressCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0003-2478-4121
Yuan LuCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0001-6884-8057
Devin Chandler-MilitelloCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-3766-8368
Abdellatif BenraissCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-0325-6234
Maiken NedergaardCenter for Translational Neuromedicine, Departments of Neurosurgery and Neurology, University of Rochester Medical Center, Rochester, NY 14642, USA. nedergaard@urmc.rochester.edu.ORCID 0000-0002-9254-5360
University of Rochester Medical Center · USChildren's National · US

Funding

Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
Para-Vascular Basis of Small Vessel DiseaseR01NS100366 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2016 to 2020
$3.8M
Characterizing the glymphatic peri-vascular connectome and its disruption in ADRF1AG053991 · NIA · YALE UNIVERSITY · PI BENVENISTE, HELENE D, NEDERGAARD, MAIKEN · 2016 to 2016
$3.4M
Age and AD related bottlenecks in glymphatic-lymphatic waste transportRF1AG057575 · NIA · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2017 to 2017
$3.2M
Failure of metabolite clearance in a model of multi-lacunar infarctsR01NS078167 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2012 to 2016
$1.8M
The glymphatic system, a new concept in glia biologyR01NS078304 · NINDS · UNIVERSITY OF ROCHESTER · PI NEDERGAARD, MAIKEN · 2012 to 2016
$1.7M
Postdoctoral Training in Developmental Disabilities ResearchT32HD046388 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2006 to 2016
$1.5M
Glymphatic function in a transgenic rat model of Alzheimer's diseaseR01AG048769 · NIA · UNIVERSITY OF ROCHESTER · PI BENVENISTE, HELENE D, NEDERGAARD, MAIKEN · 2014 to 2018
$1.4M
Astrocytes role in lipid mediated synaptic activityF31NS073390 · NINDS · UNIVERSITY OF ROCHESTER · PI SMITH, NATHAN A · 2011 to 2012
$84k
NIA NIH HHS R01 AG048769NIA NIH HHS RF1 AG053991NIA NIH HHS RF1 AG057575NICHD NIH HHS T32 HD046388NICHD NIH HHS U54 HD090257NINDS NIH HHS F31 NS073390NINDS NIH HHS R01 NS078167NINDS NIH HHS R01 NS078304NINDS NIH HHS R01 NS100366
6 · The paper itself

Abstract

Fluorescent Ca

Indexed as

Adenosine TriphosphateAniline CompoundsAnimalsAstrocytesCells, CulturedEnzyme InhibitorsFluorescent DyesFura-2Heterocyclic Compounds, 3-RingHumansKidney Tubules, ProximalMiceMice, Inbred C57BLMyocytes, CardiacNeuronsPotassiumAdenosine TriphosphateAniline CompoundsEnzyme InhibitorsFluo 4Fluorescent DyesFura-2Heterocyclic Compounds, 3-RingPotassiumrhod-2Sodium-Potassium-Exchanging ATPaseXanthenes

Identifiers

PMID29382785
PMCPMC6190706
OpenAlexW2785469511

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.