Evidence map›Paper›PMID 29382671›Full record

ArticleCancer immunology research2018

Mast Cell-Dependent CD8

Sobha R Bodduluri, Steven Mathis, Paramahamsa Maturu, Elangovan Krishnan, Shuchismita R Satpathy, Paula M Chilton, Thomas C Mitchell, Sergio Lira, Massimo Locati, Alberto Mantovani and 2 more

Open access · greenAbstract read
In one paragraph

Article in Cancer immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Deciphering the Role of Mast Cells in HPV-Related Cancers.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Chemoradiotherapy-induced ACKR2Cell reports. Medicine · 2024
    Article
  9. Review
  10. Article
  11. Mast cells: a double-edged sword in inflammation and fibrosis.Frontiers in cell and developmental biology · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8+ T cell function through galectin-9.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sobha R BodduluriJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky.
Steven MathisJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky.
Paramahamsa MaturuJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky.
Elangovan KrishnanJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky.
Shuchismita R SatpathyJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky.
Paula M ChiltonDepartment of Microbiology and Immunology, University of Louisville Health Sciences Center, Louisville, Kentucky.
Thomas C MitchellDepartment of Microbiology and Immunology, University of Louisville Health Sciences Center, Louisville, Kentucky.
Sergio LiraImmunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.
Massimo LocatiHumanitas Clinical and Research Center, University of Milan, Milan, Italy.
Alberto MantovaniHumanitas Clinical and Research Center, University of Milan, Milan, Italy.
Venkatakrishna R JalaJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky. H0bodd01@louisville.edu Jvrao001@louisville.edu.
Bodduluri HaribabuJames Graham Brown Cancer Center, University of Louisville Health Sciences Center, Louisville, Kentucky. H0bodd01@louisville.edu Jvrao001@louisville.edu.
Humanitas University · ITUniversity of Milan · IT

Funding

ZEBRAFISH VISUAL FUNCTION RECOVERY FOLLOWING OPTIC NERVE DAMAGEP20RR016481 · NCRR · UNIVERSITY OF LOUISVILLE · PI BARTON, HAZEL A · 2001 to 2011
$34.8M
PROJ 12: STEM CELL-BASED VACCINE FOR CANCER PROPHYLAXISP20RR018733 · NCRR · UNIVERSITY OF LOUISVILLE · PI TRENT, JOHN O · 2003 to 2011
$18.9M
Molecular pathogenesis of intestinal serrated polypsR01CA161373 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LIRA, SERGIO A. · 2011 to 2020
$3.7M
Role of leukotriene B4 receptors in the interplay of inflammation and infectionR01CA138623 · NCI · UNIVERSITY OF LOUISVILLE · PI BODDULURI, HARIBABU · 2009 to 2013
$1.5M
NCI NIH HHS R01 CA138623NCRR NIH HHS P20 RR016481NCRR NIH HHS P20 RR018733
6 · The paper itself

Abstract

The presence of mast cells in some human colorectal cancers is a positive prognostic factor, but the basis for this association is incompletely understood. Here, we found that mice with a heterozygous mutation in the

Indexed as

Adenomatous Polyposis Coli ProteinAnimalsCD8-Positive T-LymphocytesChemokine Receptor D6FemaleImmunologic SurveillanceIntestinal NeoplasmsLeukotriene B4MaleMast CellsMice, TransgenicReceptors, ChemokineReceptors, Leukotriene B4Ackr2 protein, mouseAdenomatous Polyposis Coli Proteinadenomatous polyposis coli protein, mouseChemokine Receptor D6Leukotriene B4Ltb4r1 protein, mouseReceptors, ChemokineReceptors, Leukotriene B4

Identifiers

PMID29382671
PMCPMC9580996
OpenAlexW2787795692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.