Evidence map›Paper›PMID 29382668›Full record

ArticleCMAJ open2018

The relation between publication rate and financial conflict of interest among physician authors of high-impact oncology publications: an observational study.

Victoria Kaestner, Jonathan B Edmiston, Vinay Prasad

Abstract read
In one paragraph

Article in CMAJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Cancer drug development: The missing links.Experimental biology and medicine (Maywood, N.J.) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Victoria KaestnerAffiliations: Division of Hematology and Medical Oncology (Kaestner, Prasad), Knight Cancer Institute, Oregon Health and Science University; School of Medicine (Edmiston), Oregon Health and Science University; Department of Preventive Medicine and Public Health (Prasad); Center for Health Care Ethics (Prasad), Oregon Health and Science University, Portland, Ore.
Jonathan B EdmistonAffiliations: Division of Hematology and Medical Oncology (Kaestner, Prasad), Knight Cancer Institute, Oregon Health and Science University; School of Medicine (Edmiston), Oregon Health and Science University; Department of Preventive Medicine and Public Health (Prasad); Center for Health Care Ethics (Prasad), Oregon Health and Science University, Portland, Ore.
Vinay PrasadAffiliations: Division of Hematology and Medical Oncology (Kaestner, Prasad), Knight Cancer Institute, Oregon Health and Science University; School of Medicine (Edmiston), Oregon Health and Science University; Department of Preventive Medicine and Public Health (Prasad); Center for Health Care Ethics (Prasad), Oregon Health and Science University, Portland, Ore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the abundant research on financial conflict of interest regarding provider behaviour and the interpretation and results of research, little is known about the relation between these conflicts in academia and the trajectory of one's academic career. We performed a study to examine whether the presence of financial ties to drug makers among academics is associated with research productivity.

methodsWe hand-searched 3 high-impact general medical journals (

resultsOur sample consisted of 435 physicians who had authored a median of 140 publications, earning a median h-index of 36 and a median of 5639 citations. The median total of general payments from 2013 to 2015 was US$3282 (range $0-$3.4 million), and the median amount of research payments was US$3500 (range $0-$23 million). General payments were associated with contemporary publications, with an increase of 1.99 papers (95% confidence interval [CI] 1.1 to 2.9) per $10 000 in payments. This association persisted in multivariate analysis after adjustment for prior publications, seniority and research payments (0.84 papers [95% CI 0.15 to 1.5] per $10 000 in payments).

interpretationThe findings suggest that there is a positive association between personal payments from drug makers and publications, and that this association persists after adjustment for prior publications, time since medical school graduation and research payments.

Identifiers

PMID29382668
PMCPMC5878961

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