Evidence map›Paper›PMID 29382628›Full record

ArticleJMIR research protocols2018

Using the Inflammacheck Device to Measure the Level of Exhaled Breath Condensate Hydrogen Peroxide in Patients With Asthma and Chronic Obstructive Pulmonary Disease (The EXHALE Pilot Study): Protocol for a Cross-Sectional Feasibility Study.

Daniel M Neville, Carole Fogg, Thomas P Brown, Thomas L Jones, Eleanor Lanning, Paul Bassett, Anoop J Chauhan

Open access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Daniel M NevilleDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0001-5222-1516
Carole FoggDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0002-3000-6185
Thomas P BrownDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0001-7336-4719
Thomas L JonesDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0002-6324-7540
Eleanor LanningDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0001-6718-4949
Paul BassettStats Consultancy Ltd, Amersham, United Kingdom.ORCID http://orcid.org/0000-0001-7830-4563
Anoop J ChauhanDepartment of Respiratory Research & Innovation, Portsmouth Hospitals NHS Trust, Portsmouth, United Kingdom.ORCID http://orcid.org/0000-0003-4044-6114
Portsmouth Hospitals NHS Trust · GBQueen Alexandra Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma and Chronic Obstructive Pulmonary Disease (COPD) are common conditions that affect over 5 million people in the United Kingdom. These groups of patients suffer significantly from breathlessness and recurrent exacerbations that can be difficult to diagnose and go untreated. A common feature of COPD and asthma is airway inflammation that increases before and during exacerbations. Current methods of assessing airway inflammation can be invasive, difficult to perform, and are often inaccurate. In contrast, measurement of exhaled breath condensate (EBC) hydrogen peroxide (H

objectiveThe aim of this study was to explore the use of a new handheld device (called Inflammacheck) in measuring H

methodsWe will perform a cross-sectional, feasibility, pilot study of EBC H

resultsThis study's recruitment is ongoing; it is anticipated that the results will be available in 2018.

conclusionsThe EXhaled Hydrogen peroxide As a marker of Lung diseasE (EXHALE) pilot study will provide an evaluation of a new method of measuring EBC H

Indexed as

asthmabiomarkersCOPDmedical devicereexhalation

Identifiers

PMID29382628
PMCPMC5811652
OpenAlexW2785432020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.