Evidence map›Paper›PMID 29382173›Full record

ArticleInternational journal of molecular sciences2018

Anti-Cancerous Effect of Inonotus taiwanensis Polysaccharide Extract on Human Acute Monocytic Leukemia Cells through ROS-Independent Intrinsic Mitochondrial Pathway.

Tsai-Ling Chao, Ting-Yin Wang, Chin-Huei Lee, Shuenn-Jiun Yiin, Chun-Te Ho, Sheng-Hua Wu, Huey-Ling You, Chi-Liang Chern

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Epimedium Polysaccharide Ameliorates Benzene-Induced Aplastic Anemia in Mice.Evidence-based complementary and alternative medicine : eCAM · 2020
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Tsai-Ling ChaoDepartments of Laboratory Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. tsaeling@cgmh.org.tw.
Ting-Yin WangDepartment of Laboratory Medicine, Yunlin Christian Hospital, Yunlin 648, Taiwan. phoebe82825@gmail.com.
Chin-Huei LeeDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung 804, Taiwan. 5MT970038@live.fy.edu.tw.
Shuenn-Jiun YiinDepartment of Nursing, Tajen University, Pintung 907, Taiwan. yiinsj@tajen.edu.tw.
Chun-Te HoGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan. homenjer@gmail.com.
Sheng-Hua WuDepartment of Biology, National Museum of Natural Science, Taichung 404, Taiwan. shwu@mail.nmns.edu.tw.
Huey-Ling YouDepartments of Laboratory Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan. youhling@cgmh.org.tw.
Chi-Liang ChernDepartment of Medical Laboratory Science and Biotechnology, Fooyin University, Kaohsiung 831, Taiwan. mt115@fy.edu.tw.
Fooyin University · TWKaohsiung Chang Gung Memorial Hospital · TWNational Museum of Natural Science · TWNational Sun Yat-sen University · TWNational Yunlin University of Science and Technology · TWTaipei Medical University · TWTajen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute leukemia is one of the commonly diagnosed neoplasms and causes human death. However, the treatment for acute leukemia is not yet satisfactory. Studies have shown that mushroom-derived polysaccharides display low toxicity and have been used clinically for cancer therapy. Therefore, we set out to evaluate the anti-cancerous efficacy of a water-soluble polysaccharide extract from

Indexed as

ApoptosisAcetylcysteineAntineoplastic AgentsAutophagyBasidiomycotaCaspase InhibitorsCell Line, TumorDNA FragmentationEndodeoxyribonucleasesFungal PolysaccharidesHumansLeukemia, MyeloidMembrane Potential, MitochondrialMitochondriaMonocytesReactive Oxygen SpeciesAcetylcysteineAntineoplastic AgentsCaspase InhibitorsEndodeoxyribonucleasesendonuclease GFungal PolysaccharidesReactive Oxygen Speciesapoptosisendonuclease Ghuman acute monocytic leukemia cell lineInonotus taiwanensis

Identifiers

PMID29382173
PMCPMC5855615
OpenAlexW2788129450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.