Evidence map›Paper›PMID 29382136›Full record

ArticleSensors (Basel, Switzerland)2018

A New Strategy Involving the Use of Peptides and Graphene Oxide for Fluorescence Turn-on Detection of Proteins.

Huan Shi, Bibo Zhang, Shuwen Liu, Chunyan Tan, Ying Tan, Yuyang Jiang

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huan ShiDepartment of Chemistry, Tsinghua University, Beijing 100084, China. shi-h16@mails.tsinghua.edu.cn.
Bibo ZhangDepartment of Chemistry, Tsinghua University, Beijing 100084, China. zbb14@mails.tsinghua.edu.cn.
Shuwen LiuDepartment of Chemistry, Tsinghua University, Beijing 100084, China. liusw15@mails.tsinghua.edu.cn.
Chunyan TanDepartment of Chemistry, Tsinghua University, Beijing 100084, China. tancy@sz.tsinghua.edu.cn.
Ying TanDepartment of Chemistry, Tsinghua University, Beijing 100084, China. tan.ying@sz.tsinghua.edu.cn.
Yuyang JiangThe State Key Laboratory Breeding Base-Shenzhen Key Laboratory of Chemical Biology, the Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China. jiangyy@sz.tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of proteins is of great biological significance as disease biomarkers in early diagnosis, prognosis tracking and therapeutic evaluation. Thus, we developed a simple, sensitive and universal protein-sensing platform based on peptide and graphene oxide (GO). The design consists of a fluorophore (TAMRA, TAM), a peptide containing eight arginines and peptide ligand that could recognize the target protein, and GO used as a quencher. To demonstrate the feasible use of the sensor for target detection, Bcl-xL was evaluated as the model target. The sensor was proved to be sensitive and applied for the detection of the target proteins in buffer, 2% serum and living cells.

Indexed as

Biosensing TechniquesGraphiteOxidesPeptidesProteinsSpectrometry, FluorescenceGraphiteOxidesPeptidesProteinsarigininesGOpeptideselectivitysensitivity

Identifiers

PMID29382136
PMCPMC5855184

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.