Evidence map›Paper›PMID 29382116›Full record

ArticleSensors (Basel, Switzerland)2018

An Improved Method for Magnetic Nanocarrier Drug Delivery across the Cell Membrane.

Behzad Mehrafrooz, Maysam Z Pedram, Ebrahim Ghafar-Zadeh

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Modulation of Proteinoid Electrical Spiking Activity with Magnetic Nanoparticles.Langmuir : the ACS journal of surfaces and colloids · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Behzad MehrafroozDepartment of Mechanical Engineering, K.N. Toosi University of Technology, Tehran 16315-1355, Iran. behzadmehrafrooz@gmail.com.
Maysam Z PedramFaculty of Electrical and Computer Engineering, K.N. Toosi University of Technology, Tehran 16315-1355, Iran. mzpedram@kntu.ac.ir.
Ebrahim Ghafar-ZadehDepartement of Electrical Engineering and Computer Science, York University, Toronto, ON M3J1P3, Canada. egz@cse.yorku.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the crucial issues in the pharmacological field is developing new drug delivery systems. The main concern is to develop new methods for improving the drug delivery efficiencies such as low disruptions, precise control of the target of delivery and drug sustainability. Nowadays, there are many various methods for drug delivery systems. Carbon-based nanocarriers are a new efficient tool for translocating drug into the defined area or cells inside the body. These nanocarriers can be functionalized with proteins, peptides and used to transport their freight to cells or defined areas. Since functionalized carbon-based nanocarriers show low toxicity and high biocompatibility, they are used in many nanobiotechnology fields. In this study, different shapes of nanocarrier are investigated, and the suitable magnetic field, which is applied using MRI for the delivery of the nanocarrier, is proposed. In this research, based on the force required to cross the membrane and MD simulations, the optimal magnetic field profile is designed. This optimal magnetic force field is derived from the mathematical model of the system and magnetic particle dynamics inside the nanocarrier. The results of this paper illustrate the effects of the nanocarrier's shapes on the percentage of success in crossing the membrane and the optimal required magnetic field.

Indexed as

Cell MembraneDrug CarriersDrug Delivery SystemsMagnetic FieldsNanostructuresDrug Carriersdrug deliverymagnetic fieldmagnetic nanocarriermagnetic resonance imaging (MRI)molecular dynamics simulations

Identifiers

PMID29382116
PMCPMC5856133

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.