Evidence map›Paper›PMID 29382109›Full record

ReviewMolecules (Basel, Switzerland)2018

Chiral Drug Analysis in Forensic Chemistry: An Overview.

Cláudia Ribeiro, Cristiana Santos, Valter Gonçalves, Ana Ramos, Carlos Afonso, Maria Elizabeth Tiritan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Interpol review of controlled substances 2016-2019.Forensic science international. Synergy · 2020
    Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cláudia RibeiroInstitute of Research and Advanced Training in Health Sciences and Technologies , Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal. claudia.ribeiro@iucs.cespu.pt.ORCID 0000-0001-7245-4552
Cristiana SantosInstitute of Research and Advanced Training in Health Sciences and Technologies , Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal. cristiana.s@live.com.pt.ORCID 0000-0002-1898-5755
Valter GonçalvesLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto , Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal. valter.cma@gmail.com.ORCID 0000-0002-4436-2834
Ana RamosInstitute of Science and Innovation in Mechanical and Industrial Engineering (INEGI), Faculty of Engineering of the University of Porto, Rua Dr. Roberto Frias, 400, 4200-465 Porto, Portugal. shortinha.sa@gmail.com.
Carlos AfonsoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Edifício do Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n, 4050-208 Matosinhos, Portugal. cafonso@ff.up.pt.
Maria Elizabeth TiritanInstitute of Research and Advanced Training in Health Sciences and Technologies , Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal. elizabeth.tiritan@iucs.cespu.pt.ORCID 0000-0003-3320-730X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many substances of forensic interest are chiral and available either as racemates or pure enantiomers. Application of chiral analysis in biological samples can be useful for the determination of legal or illicit drugs consumption or interpretation of unexpected toxicological effects. Chiral substances can also be found in environmental samples and revealed to be useful for determination of community drug usage (sewage epidemiology), identification of illicit drug manufacturing locations, illegal discharge of sewage and in environmental risk assessment. Thus, the purpose of this paper is to provide an overview of the application of chiral analysis in biological and environmental samples and their relevance in the forensic field. Most frequently analytical methods used to quantify the enantiomers are liquid and gas chromatography using both indirect, with enantiomerically pure derivatizing reagents, and direct methods recurring to chiral stationary phases.

Indexed as

Chromatography, GasChromatography, LiquidForensic SciencesPharmaceutical PreparationsPharmaceutical Preparationschiral drugsenantiomersforensic chemistryillicit drugspharmaceuticals

Identifiers

PMID29382109
PMCPMC6017579

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.