Evidence map›Paper›PMID 29382040›Full record

ArticleMolecules (Basel, Switzerland)2018

Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in Vitro Antitrypanosomal Activity.

Njogu M Kimani, Josphat C Matasyoh, Marcel Kaiser, Reto Brun, Thomas J Schmidt

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Plants (Basel, Switzerland) · 2023
    Article
  6. Plant Terpenoids as Hit Compounds against Trypanosomiasis.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Article
  9. Antitrypanosomal Activity of Sesquiterpene Lactones fromMolecules (Basel, Switzerland) · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Njogu M KimaniInstitute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus Corrensstraße 48, D-48149 Münster, Germany. m_kima01@uni-muenster.de.ORCID 0000-0002-5171-1940
Josphat C MatasyohDepartment of Chemistry, Egerton University, P.O. Box 536, Egerton 20115, Kenya. josphat2001@yahoo.com.
Marcel KaiserSwiss Tropical and Public Health Institute (Swiss TPH), Socinstr. 57, CH-4051 Basel, Switzerland. marcel.kaiser@unibas.ch.
Reto BrunSwiss Tropical and Public Health Institute (Swiss TPH), Socinstr. 57, CH-4051 Basel, Switzerland. reto.brun@unibas.ch.
Thomas J SchmidtInstitute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus Corrensstraße 48, D-48149 Münster, Germany. thomschm@uni-muenster.de.ORCID 0000-0003-2634-9705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the endeavor to obtain new antitrypanosomal agents, particularly sesquiterpene lactones, from Kenyan plants of the family Asteraceae,

Indexed as

AnimalsCell Line, TransformedHeterocyclic Compounds, 4 or More RingsInhibitory Concentration 50LactonesMyoblastsPlant ExtractsPlant LeavesRatsSesquiterpenesTrypanocidal AgentsTrypanosoma brucei rhodesienseVernonia11,13-dihydrovernolideHeterocyclic Compounds, 4 or More RingsLactonesPlant ExtractsSesquiterpenesTrypanocidal Agentsvernodalinvernodalolvernolideantitrypanosomal activityAsteraceaesesquiterpene lactonesTrypanosoma brucei rhodesienseVernonia cinerascens

Identifiers

PMID29382040
PMCPMC6017816

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.