Evidence map›Paper›PMID 29381930›Full record

Observational studyMedicine2017

Chronic autoimmune disorders are increased in coeliac disease: A case-control study.

Stefano Bibbò, Giovanni Mario Pes, Paolo Usai-Satta, Roberta Salis, Sara Soro, Bianca Maria Quarta Colosso, Maria Pina Dore

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
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  8. Article
  9. Conundrum for Psoriasis and Thyroid Involvement.International journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
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  15. Review
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  17. Review
  18. Article
  19. Fecal Microbiota Signatures in Celiac Disease Patients With Poly-Autoimmunity.Frontiers in cellular and infection microbiology · 2020
    Article
  20. The spectrum of clinical and subclinical endocrinopathies in treatment-naïve patients with celiac disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefano BibbòDepartment of Clinical and Experimental Medicine, University of Sassari, Sassari Gastroenterology Unit, Brotzu Hospital, Cagliari, Italy.
Giovanni Mario Pes
Paolo Usai-Satta
Roberta Salis
Sara Soro
Bianca Maria Quarta Colosso
Maria Pina Dore
University of Sassari · ITAzienda Ospedaliera G. Brotzu · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coeliac disease (CD) is an autoimmune disorder of the small bowel associated with increased risk of additional autoimmune diseases (ADs).To investigate the prevalence of ADs in a population of adult coeliac patients.This was a retrospective case-control study. Data from coeliac patients and controls referred to a tertiary center between 2013 and 2016 were collected. The frequency of ADs and the unadjusted and adjusted odds ratios (ORs) for age, gender, disease duration, and body mass index with their 95% confidence intervals (CIs) were evaluated.Two hundred fifty-five patients with CD (median age 37.1 years; 206 women) were matched with 250 controls. ADs were more frequent (35.3%) in coeliac patients than in controls (15.2%). Adjusted ORs for the presence of only 1, at least 1, and more than 1 AD were 3.13 (95% CI 1.81-5.42, P < .0001), 3.31 (95% CI 2.00-5.46, P < .0001), and 3.93 (95% CI 1.49-10.36, P = .006), respectively. Hashimoto thyroiditis was the most prevalent AD (24.3% vs. 10%) OR = 2.55 (95% CI 1.39-4.70, P < .0001), followed by psoriasis (4.3% vs. 1.6%), type 1 diabetes (2.7% vs. 0.4%), and Sjögren syndrome (2.4% vs. 0.4%).These findings suggest a need for a careful surveillance of autoimmune status, especially for Hashimoto thyroiditis in patients with celiac disease.

Indexed as

Autoimmune DiseasesCeliac DiseaseHashimoto DiseaseAdultAutoimmunityCase-Control StudiesFemaleHumansItalyMalePrevalenceRetrospective Studies

Identifiers

PMID29381930
PMCPMC5708929
OpenAlexW2769165155

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.