Evidence map›Paper›PMID 29381790›Full record

ArticleThe American journal of clinical nutrition2018

Adherence to a healthy eating index for pregnant women is associated with lower neonatal adiposity in a multiethnic Asian cohort: the Growing Up in Singapore Towards healthy Outcomes (GUSTO) Study.

Ai-Ru Chia, Mya-Thway Tint, Chad Yixian Han, Ling-Wei Chen, Marjorelee Colega, Izzuddin M Aris, Mei-Chien Chua, Kok-Hian Tan, Fabian Yap, Lynette Pei-Chi Shek and 5 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01174875 (Developmental Pathways to Health and Disease), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01174875 active not recruitingnot on this map

Developmental Pathways to Health and Disease: Metabolic, Neurodevelopmental and Related Outcomes

TypeobservationalSponsorNational University Hospital, SingaporeRan2009 to 2029Enrolled1,247ConditionsMetabolic Diseases, Neurological and Mental Health Conditions, Genetic Predisposition, Skin Condition
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Ai-Ru ChiaDepartments of Obstetrics and Gynecology and Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mya-Thway TintDepartments of Obstetrics and Gynecology and Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chad Yixian HanDepartment of Dietetics and Nutrition, Ng Teng Fong General Hospital, National University Health System, Singapore.
Ling-Wei ChenDepartments of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Marjorelee ColegaSingapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore.
Izzuddin M ArisSingapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore.
Mei-Chien ChuaDepartments of Neonatology, Maternal Fetal Medicine, Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore.
Kok-Hian TanDepartments of Maternal Fetal Medicine, Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore.
Fabian YapDepartments of Pediatrics, and Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore.
Lynette Pei-Chi ShekDepartments of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yap-Seng ChongDepartments of Obstetrics and Gynecology and Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Keith M GodfreyMedical Research Council Lifecourse Epidemiology Unit and National Institute for Health Research Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton National Health Service Foundation Trust, Southampton, United Kingdom.
Marielle V FortierDepartments of Diagnostic and Interventional Imaging, KK Women's and Children's Hospital, Singapore.
Yung Seng LeeDepartments of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mary Foong-Fong ChongSingapore Institute for Clinical Sciences, Agency for Science, Technology, and Research, Singapore.
National University of Singapore · SGAgency for Science, Technology and Research · SGKK Women's and Children's Hospital · SGNational Health Service · GBNg Teng Fong General Hospital · SG

Funding

British Heart Foundation RG/15/17/31749Medical Research Council MC_U147574222Medical Research Council MC_U147574226Medical Research Council MC_UP_A620_1017Medical Research Council MC_UU_12011/4Medical Research Council MR/J000094/1
6 · The paper itself

Abstract

Background: Evidence linking maternal diet quality during pregnancy with infant birth outcomes is limited in Asia. Objective: We investigated the association of maternal diet quality with the risk of preterm birth, offspring birth size, and adiposity in a multiethnic Asian birth cohort. Design: Dietary intakes of 1051 pregnant women were ascertained at 26-28 wk of gestation with the use of 24-h recalls and 3-d food diaries, from which diet quality (score range: 0-100) was measured by the Healthy Eating Index for pregnant women in Singapore (HEI-SGP). Gestational age was established by first-trimester ultrasound dating scan. Neonatal weight and length were measured at birth. Body composition was assessed by air displacement plethysmography in a subset of infants (n = 313) within 72 h after birth, and abdominal adiposity was assessed by MRI (n = 316) within the first 2 wk of life. Associations were assessed by multivariable linear regression for continuous outcomes and logistic regression for preterm birth. Results: The mean ± SD maternal HEI-SGP score was 52.1 ± 13.6. Maternal diet quality during pregnancy was not associated with preterm birth or birth weight. Greater adherence to the HEI-SGP (per 10-point increment in HEI-SGP score) was associated with longer birth length [β (95% CI): 0.14 (0.03, 0.24 cm)], lower body mass index (in kg/m2) at birth [-0.07 (-0.13, -0.01)], lower sum of triceps and subscapular skinfold thickness [-0.15 (-0.26, -0.05 mm)], lower percentage body fat [-0.52% (-0.84%, -0.20%)], lower fat mass [-17.23 (-29.52, -4.94 g)], lower percentage abdominal superficial subcutaneous adipose tissue [-0.16% (-0.30%, -0.01%)], and lower percentage deep subcutaneous adipose tissue [-0.06% (-0.10%, -0.01%)]. Conclusions: Higher maternal diet quality during pregnancy was associated with longer birth length and lower neonatal adiposity but not with birth weight and preterm birth. These findings warrant further investigation in independent studies. This trial was registered at clinicaltrials.gov as NCT01174875.

Indexed as

AdiposityDiet, HealthyMaternal Nutritional Physiological PhenomenaPatient ComplianceAdolescentAdultAsian PeopleBirth WeightBody CompositionBody Mass IndexDiet RecordsExerciseFemaleFood QualityHumansLost to Follow-Upadipositybirth weightdiet qualitymaternal dietpreterm birth

Identifiers

PMID29381790
PMCPMC5972656
OpenAlexW2773801359

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.