ArticleMenopause (New York, N.Y.)2018
What's in a name: are menopausal "hot flashes" a symptom of menopause or a manifestation of neurovascular dysregulation?
Article in Menopause (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes.Experimental physiology · 2026Article
- Effects of a healthy diet based on seed-rich vegetables on the gut microbiota and intrinsic brain activity in perimenopausal women: A pilot study on cognitive improvement.Scientific reports · 2025Article
- Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome.mSystems · 2024Article
- Menopausal Vasomotor Symptoms and Subclinical Atherosclerotic Cardiovascular Disease: A Population-Based Study.Journal of the American Heart Association · 2024Article
- Risks and benefits of hormone therapy after menopause for cognitive decline and dementia: A conceptual review.Maturitas · 2024Review
- Article
- Zuogui and Yougui pills improve perimenopausal syndrome regulation of apoptosis in mice.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023Article
- The relationship between menopausal syndrome and gut microbes.BMC women's health · 2022Article
- Hypertensive disorders of pregnancy and menopausal symptoms: a cross-sectional study from the data registry on experiences of aging, menopause, and sexuality.Menopause (New York, N.Y.) · 2020Article
- Effect of Combined Herbal Capsule Menohelp on Hot Flashes and Night Sweats in Postmenopausal Women: A Single-Blind Randomized Controlled Trial.Journal of menopausal medicine · 2020Article
- Sleep Quality in Autism from Adolescence to Old Age.Autism in adulthood · 2020Article
- Life-Course Reproductive History and Cardiovascular Risk Profile in Late Mid-Life: The CARDIA Study.Journal of the American Heart Association · 2020Article
- Multimorbidity After Surgical Menopause Treated with Individualized Classical Homeopathy: A Case Report.Clinical medicine insights. Case reports · 2020Article
- Complementary and alternative treatment methods for menopausal hot flashes used in Turkey.African health sciences · 2019Article
- Sympathetic neural responsiveness to sleep deprivation in older adults: sex differences.American journal of physiology. Heart and circulatory physiology · 2019Article
- A qualitative assessment of health behaviors and experiences during menopause: A cross-sectional, observational study.Maturitas · 2018Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Hot flashes have typically been classified as "symptoms of menopause" that should be tolerated or treated until they resolve. However, mounting evidence points to hot flashes as a manifestation of one or several underlying pathophysiological processes. Associations exist between the presence, timing of onset, severity, and duration of hot flashes, and the risk of several neurological (affecting sleep, mood, and cognition) and cardiovascular conditions. In addition, four consistent patterns of vasomotor disturbances have been identified across different countries, making it unlikely that these patterns are solely explained by socioeconomic or cultural factors. The changing hormonal environment of menopause may unmask differences in the autonomic neurovascular control mechanisms that put an individual woman at risk for chronic conditions of aging. These differences may have a genetic basis or may be acquired across the life span and are consistent with the variability of the clinical manifestations of aging observed in women after bilateral oophorectomy. It is time to investigate the pathophysiological mechanisms underlying the four patterns of vasomotor symptoms more closely, and to shift from describing hot flashes as symptoms to be tolerated to manifestations of an underlying autonomic neurovascular dysregulation that need to be addressed.
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