Evidence map›Paper›PMID 29381374›Full record

Trial reportAmerican journal of physiology. Endocrinology and metabolism2018

Humans with obesity have disordered brain responses to food images during physiological hyperglycemia.

Renata Belfort-DeAguiar, Dongju Seo, Cheryl Lacadie, Sarita Naik, Christian Schmidt, Wai Lam, Janice Hwang, Todd Constable, Rajita Sinha, Robert S Sherwin

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of physiology. Endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Renata Belfort-DeAguiarSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Dongju SeoDepartment of Psychiatry, Yale University School of Medicine , New Haven, Connecticut.
Cheryl LacadieDepartment of Radiology, Yale University School of Medicine , New Haven, Connecticut.
Sarita NaikSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Christian SchmidtSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Wai LamSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Janice HwangSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Todd ConstableDepartment of Radiology, Yale University School of Medicine , New Haven, Connecticut.
Rajita SinhaDepartment of Psychiatry, Yale University School of Medicine , New Haven, Connecticut.
Robert S SherwinSection of Endocrinology, Department of Internal Medicine, Yale University School of Medicine , New Haven, Connecticut.
Yale University · US

Funding

Yale Diabetes Research CenterP30DK045735 · NIDDK · YALE UNIVERSITY · PI GERALD I SHULMAN · 1993 to 2026
$44.0M
Multimodal Neuroimaging of Stress, Arousal and Alcoholism RiskK08AA023545 · NIAAA · YALE UNIVERSITY · PI SEO, DONGJU · 2015 to 2019
$948k
Investigating the polyol pathway in the human brainK23DK109284 · NIDDK · YALE UNIVERSITY · PI HWANG, JANICE JIN · 2016 to 2019
$758k
NIAAA NIH HHS K08 AA023545NIDDK NIH HHS K23 DK109284NIDDK NIH HHS P30 DK045735
6 · The paper itself

Abstract

Blood glucose levels influence brain regulation of food intake. This study assessed the effect of mild physiological hyperglycemia on brain response to food cues in individuals with obesity (OB) versus normal weight individuals (NW). Brain responses in 10 OB and 10 NW nondiabetic healthy adults [body mass index: 34 (3) vs. 23 (2) kg/m

Indexed as

FoodAdministration, IntravenousAdultBrainBrain DiseasesCognitionCuesFemaleGlucoseHumansHyperglycemiaMagnetic Resonance ImagingMaleObesityPhotic StimulationYoung AdultGlucosebrain activityfMRIfood cueshyperglycemiaobesity

Identifiers

PMID29381374
PMCPMC6048387
OpenAlexW2786695689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.