Evidence map›Paper›PMID 29380953›Full record

ArticlePhysiological reports2018

Nominal carbonic anhydrase activity minimizes airway-surface liquid pH changes during breathing.

Ian M Thornell, Xiaopeng Li, Xiao Xiao Tang, Christian M Brommel, Philip H Karp, Michael J Welsh, Joseph Zabner

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Comparative Analysis of Carbonic Anhydrase-II Expression Across Undescended Testes Sprague Dawley Model with Coenzyme Q10 Treatment.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2025
    Article
  3. The pH-sensitive translocation of V-ATPase in the small airway of cystic fibrosis pigs.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  4. Ciliary Motility Decreased by a COInternational journal of molecular sciences · 2024
    Article
  5. Evaluation of Human Carbonic Anhydrase II (CA-II) Concentration Using ELISA: Insights into Optical Density's Role in Biomarker Quantification for Cryptorchidism Research.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs.American journal of respiratory cell and molecular biology · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ian M ThornellDepartment of Internal Medicine, University of Iowa, Iowa City, IA.ORCID 0000-0001-5535-2925
Xiaopeng LiDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
Xiao Xiao TangDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
Christian M BrommelDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
Philip H KarpDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
Michael J WelshDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
Joseph ZabnerDepartment of Internal Medicine, University of Iowa, Iowa City, IA.
University of Iowa · US

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Vector CoreP01HL051670 · NHLBI · UNIVERSITY OF IOWA · PI MCCRAY, PAUL B · 1993 to 2019
$36.5M
Respiratory virus infection in early cystic fibrosis lung diseaseP01HL091842 · NHLBI · UNIVERSITY OF IOWA · PI STOLTZ, DAVID A · 2008 to 2022
$34.2M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
NHLBI NIH HHS P01 HL051670NHLBI NIH HHS P01 HL091842NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

The airway-surface liquid pH (pH

Indexed as

Hydrogen-Ion ConcentrationRespirationAnimalsAnimals, NewbornCarbonic AnhydrasesRespiratory MucosaSwineCarbonic AnhydrasesAcid-baseairway epitheliumairway-surface liquidcarbonic anhydrase

Identifiers

PMID29380953
PMCPMC5789725
OpenAlexW2788019040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.