Evidence map›Paper›PMID 29380952›Full record

Trial reportPhysiological reports2018

Acute ingestion of dietary nitrate increases muscle blood flow via local vasodilation during handgrip exercise in young adults.

Jennifer C Richards, Matthew L Racine, Christopher M Hearon, Megan Kunkel, Gary J Luckasen, Dennis G Larson, Jason D Allen, Frank A Dinenno

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05143879 (Long-term Effect of Combined Citrulline and Nitrate-rich Beetroot Extract Supplementation on Recovery Status in Trained Male Triathletes), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05143879 nacompletednot on this map

Long-term Effect of Combined Citrulline and Nitrate-rich Beetroot Extract Supplementation on Recovery Status in Trained Male Triathletes

TypeinterventionalSponsorBurgos NutritionRan2018 to 2021Enrolled32ConditionsCitrulline, Nitrate, AthletesArmsCitrulline, Nitrate, Nitrate plus Citrulline, Placebo
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  13. A Single Dose of Dietary Nitrate Increases Maximal Knee Extensor Angular Velocity and Power in Healthy Older Men and Women.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Trial
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  16. Review
  17. Effects of Acute Red Spinach Powder (VitaSpinachMuscles (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jennifer C RichardsHuman Cardiovascular Physiology Laboratory, Department of Health and Exercise Science, Center for Cardiovascular Research, Colorado State University, Fort Collins, Colorado, USA.
Matthew L RacineHuman Cardiovascular Physiology Laboratory, Department of Health and Exercise Science, Center for Cardiovascular Research, Colorado State University, Fort Collins, Colorado, USA.
Christopher M HearonHuman Cardiovascular Physiology Laboratory, Department of Health and Exercise Science, Center for Cardiovascular Research, Colorado State University, Fort Collins, Colorado, USA.
Megan KunkelHuman Cardiovascular Physiology Laboratory, Department of Health and Exercise Science, Center for Cardiovascular Research, Colorado State University, Fort Collins, Colorado, USA.
Gary J LuckasenMedical Center of the Rockies Foundation, Poudre Valley Health System, Loveland, Colorado, USA.
Dennis G LarsonMedical Center of the Rockies Foundation, Poudre Valley Health System, Loveland, Colorado, USA.
Jason D AllenDepartment of Kinesiology, Curry School of Education, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-5219-4423
Frank A DinennoHuman Cardiovascular Physiology Laboratory, Department of Health and Exercise Science, Center for Cardiovascular Research, Colorado State University, Fort Collins, Colorado, USA.
Colorado State University · USValley Health System · USDuke University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary nitrate (NO3-) is converted to nitrite (NO2-) and can be further reduced to the vasodilator nitric oxide (NO) amid a low O

Indexed as

Beta vulgarisAdultDietary SupplementsExerciseFemaleFruit and Vegetable JuicesHand StrengthHemodynamicsHumansMaleMuscle, SkeletalNitratesNitritesOxygen ConsumptionPlant RootsRegional Blood FlowNitratesNitritesDietary nitrateexercise hyperemiaoxygen consumption

Identifiers

PMID29380952
PMCPMC5789727
OpenAlexW2793815716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.