Evidence map›Paper›PMID 29380951›Full record

Trial reportPhysiological reports2018

Effects of short-term sex steroid suppression on dietary fat storage patterns in healthy males.

Corey A Rynders, Stacy L Schmidt, Audrey Bergouignan, Tracy J Horton, Daniel H Bessesen

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Sex Differences in Adipose Tissue Function.Endocrinology and metabolism clinics of North America · 2020
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Corey A RyndersDivision of Geriatric Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.ORCID 0000-0001-5767-6261
Stacy L SchmidtMetropolitan State University of Denver, Denver, Colorado.
Audrey BergouignanDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Tracy J HortonDepartment of Art and Art History, Colorado State University, Fort Collins, Colorado.
Daniel H BessesenDivision of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Centre National de la Recherche Scientifique · FRColorado State University · USDenver Health Medical Center · USMetropolitan State University of Denver · USUniversity of Colorado Anschutz Medical Campus · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Sex Hormones Differentially Regulate Production of Distinct Adipocyte PopulationP50HD073063 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KOHRT, WENDY M · 2012 to 2017
$5.7M
POST-PRANDIAL NUTRIENT PARTITIONING IN HUMANSK24DK002935 · NIDDK · DENVER HEALTH AND HOSPITAL AUTHORITY · PI BESSESEN, DANIEL HOLLAND · 2001 to 2010
$1.5M
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
Sex and the endocrine regulation of fuel metabolismR01DK071155 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BESSESEN, DANIEL HOLLAND · 2006 to 2009
$1.2M
Time restricted feeding and metabolic rhythms in humansK01DK113063 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI RYNDERS, COREY ALLAN · 2017 to 2021
$832k
Breaking-up sitting to offset sedentary behaviors-induced metabolic alterationsK99DK100465 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BERGOUIGNAN, AUDREY · 2014 to 2015
$179k
NCRR NIH HHS UL1 RR025780NHLBI NIH HHS T32 HL116276NICHD NIH HHS P50 HD073063NIDDK NIH HHS K01 DK113063NIDDK NIH HHS K24 DK002935NIDDK NIH HHS K99 DK100465NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK071155
6 · The paper itself

Abstract

Hypogonadism in males is associated with increased body fat and altered postprandial metabolism, but mechanisms remain poorly understood. Using a cross-over study design, we investigated the effects of short-term sex hormone suppression with or without testosterone add-back on postprandial metabolism and the fate of dietary fat. Eleven healthy males (age: 29 ± 4.5 year; BMI: 26.3 ± 2.1 kg/m

Indexed as

AdiposityAdultCross-Over StudiesDietary FatsEnergy MetabolismHumansMaleMiddle AgedPostprandial PeriodTestosteroneDietary FatsTestosteroneEnergy metabolismhypogonadismlipid metabolismpostprandial metabolismtestosterone

Identifiers

PMID29380951
PMCPMC5789716
OpenAlexW2790584202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.