Evidence map›Paper›PMID 29380931›Full record

ArticleESC heart failure2018

N-terminal pro-B-type natriuretic peptide and prognosis in Caucasian vs. Asian patients with heart failure.

Jasper Tromp, Arthur Mark Richards, Wan Ting Tay, Tiew-Hwa K Teng, Poh Shuan Daniel Yeo, David Sim, Fazlur Jaufeerally, Gerard Leong, Hean Yee Ong, Lieng Hsi Ling and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in ESC heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 5 countries.

Jasper TrompDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Arthur Mark RichardsCardiovascular Research Institute, National University Heart Centre, Singapore, Singapore.
Wan Ting TayNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Tiew-Hwa K TengNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Poh Shuan Daniel YeoTan Tock Seng Hospital, Singapore, Singapore.
David SimNational Heart Centre Singapore, 5 Hospital Drive, Singapore, 169609, Singapore.
Fazlur JaufeerallyDuke-NUS Graduate Medical School, Singapore, Singapore.
Gerard LeongChangi General Hospital, Singapore, Singapore.
Hean Yee OngKhoo Teck Puat Hospital, Singapore, Singapore.
Lieng Hsi LingCardiovascular Research Institute, National University Heart Centre, Singapore, Singapore.
Dirk J van VeldhuisenDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Tiny JaarsmaDepartment of Social and Welfare Studies, Faculty of Medical and Health Sciences, Linköping University, Linköping, Sweden.
Adriaan A VoorsDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Peter van der MeerDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Rudolf A de BoerDepartment of Cardiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
Carolyn S P LamCardiovascular Research Institute, National University Heart Centre, Singapore, Singapore.
National Heart Centre Singapore · SGNational University Heart Centre Singapore · SGUniversity of Groningen · NLChangi General Hospital · SGDuke-NUS Medical School · SGKhoo Teck Puat Hospital · SGLinköping University · SETan Tock Seng Hospital · SGThe University of Western Australia · AUUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsN-terminal pro-B-type natriuretic peptide (NT-proBNP) is the most frequently used biomarker in heart failure (HF), but its prognostic utility across ethnicities is unclear. METHODS AND

resultsThis study included 546 Caucasians with HF from the Coordinating Study Evaluating Outcomes of Advising and Counseling in Heart Failure and 578 Asians with HF from the Singapore Heart Failure Outcomes and Phenotypes study. NT-proBNP was measured at discharge after HF hospitalization. The studied outcome was a composite of all-cause mortality and HF hospitalization at 18 months. Compared with Caucasian patients, Asian patients were younger (63 ± 12 vs. 71 ± 11 years); less often female (26% vs. 39%); and had lower body mass index (26 vs. 27 kg/m

conclusionsNT-proBNP has similar prognostic performance in Asians and Caucasians with HF despite ethnic differences in known clinical determinants of plasma NT-proBNP.

Indexed as

AgedAsian PeopleBiomarkersFemaleFollow-Up StudiesHeart FailureHospitalizationHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsProspective StudiesProtein PrecursorsSingaporeStroke VolumeBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Protein PrecursorsEthnicityHeart failureHFpEFNT-proBNPPrognosis

Identifiers

PMID29380931
PMCPMC5880675
OpenAlexW2791957181

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.