ArticleThe American journal of gastroenterology2018
Hospitalizations for Autoimmune Hepatitis Disproportionately Affect Black and Latino Americans.
Article in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Immune profiling links autoimmune hepatitis to human herpesvirus 6 and relaxin receptor antigens.The Journal of experimental medicine · 2026Article
- Autoimmune Hepatitis: A Review of Molecular Mechanisms and Research Gaps in African Populations.Biology · 2026Review
- The Geoepidemiology of Autoimmune Hepatitis.Clinical reviews in allergy & immunology · 2026Review
- Autoimmune liver diseases in Latin America: Current landscape and challenges.Hepatology communications · 2026Article
- The prevalence of autoimmune hepatitis is rising: Estimates and trends from a large, multi-ethnic cohort in the United States.Hepatology communications · 2025Article
- Article
- Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.medRxiv : the preprint server for health sciences · 2024Article
- Clinical implications of gender and race in patients admitted with autoimmune hepatitis: updated analysis of US hospitals.Frontline gastroenterology · 2023Article
- Outcomes of pregnancy in autoimmune hepatitis: A population-based study.Hepatology (Baltimore, Md.) · 2022Article
- Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management.PloS one · 2022Article
- Validating a novel algorithm to identify patients with autoimmune hepatitis in an administrative database.Pharmacoepidemiology and drug safety · 2021Article
- Characteristics and Inpatient Outcomes of Primary Biliary Cholangitis and Autoimmune Hepatitis Overlap Syndrome.Journal of clinical and translational hepatology · 2021Article
- Gender and Racial Differences in Hospitalizations for Primary Biliary Cholangitis in the USA.Digestive diseases and sciences · 2021Article
- Lack of Association of Spontaneous Coronary Artery Dissection With Autoimmune Disease.Journal of the American College of Cardiology · 2020Article
- Race/Ethnicity and Insurance-Specific Disparities in In-Hospital Mortality Among Adults with Primary Biliary Cholangitis: Analysis of 2007-2014 National Inpatient Sample.Digestive diseases and sciences · 2020Article
- Regulatory T Cells in Autoimmune Hepatitis: Unveiling Their Roles in Mouse Models and Patients.Frontiers in immunology · 2020Review
- Autoimmune Hepatitis in Special Populations: In Pediatrics and Across Different Ethnicities/Races.Clinical liver disease · 2019Review
- Epidemiology and health care burden of autoimmune liver diseases in Mexico.Clinical liver diseaseReview
- Trends of Costs and Admission Rates Among Patients Admitted With Autoimmune Hepatitis: Analysis of US Hospitals Using the NIS Database.Journal of clinical and experimental hepatologyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThe healthcare burden of autoimmune hepatitis (AIH) in the United States has not been characterized. We previously showed that AIH disproportionately affects people of color in a single hospital system. The current study aimed to determine whether the same disparity occurs nationwide.
methodsWe analyzed hospitalizations with a primary discharge diagnosis corresponding to the ICD-9 code for AIH in the National Inpatient Sample between 2008 and 2012. For each racial/ethnic group, we calculated the AIH hospitalization rate per 100,000 population and per 100,000 all-cause hospitalizations, then calculated a risk ratio compared to the reference rate among whites. We used multivariable logistic regression models to assess for racial disparities and to identify predictors of in-hospital mortality during AIH hospitalizations.
resultsThe national rate of AIH hospitalization was 0.73 hospitalizations per 100,000 population. Blacks and Latinos were hospitalized for AIH at a rate 69% (P<0.001) and 20% higher (P<0.001) than whites, respectively. After controlling for age, gender, payer, residence, zip code income, region, and cirrhosis, black race was a statistically significant predictor for mortality during AIH hospitalizations (odds ratio (OR) 2.81, 95% confidence interval (CI) 1.43, 5.47).
conclusionsHospitalizations for AIH disproportionately affect black and Latino Americans. Black race is independently associated with higher odds of death during hospitalizations for AIH. This racial disparity may be related to biological, genetic, environmental, socioeconomic, and healthcare access and quality factors.
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