ArticleThe American journal of gastroenterology2018
Variation in Pathologist Classification of Colorectal Adenomas and Serrated Polyps.
Article in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A foundation systematic review of natural language processing applied to gastroenterology & hepatology.BMC gastroenterology · 2025Pooled it
- Quality indicators for colonoscopy.Gastrointestinal endoscopy · 2024Guideline
- Prevalence and Clinical Features of Sessile Serrated Polyps: A Systematic Review.Gastroenterology · 2020Pooled it
- Evaluation of serrated lesion detection using different indicators: a single-centre, community-based, retrospective cohort study.BMJ open gastroenterology · 2026Article
- Impact of Magnification Endoscopy on Diagnostic Accuracy and Confidence in Real-Time Histological Prediction of Colorectal Lesions: A Prospective Multicenter Study.Journal of gastroenterology and hepatology · 2025Article
- Colorectal Neoplasia in Vietnamese Patients Under 50 Years of Age: A Cross-Sectional Study.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Article
- Variation in Proximal Sessile Serrated Lesion Detection Rates During Non-screening Colonoscopies.Cureus · 2025Article
- Quality Indicators for Colonoscopy.The American journal of gastroenterology · 2024Article
- Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients.World journal of clinical oncology · 2024Article
- Artificial intelligence-assisted colonoscopy for adenoma and polyp detection: an updated systematic review and meta-analysis.iGIE : innovation, investigation and insights · 2023Article
- Artificial intelligence-based polyp size measurement in gastrointestinal endoscopy using the auxiliary waterjet as a reference.Endoscopy · 2023Article
- Disparate age and sex distribution of sessile serrated lesions and conventional adenomas in an outpatient colonoscopy population-implications for colorectal cancer screening?International journal of colorectal disease · 2022Observational
- Accuracy in optical diagnosis for polyps between 5 and 15 mm and its implications on surveillance. A prospective, multicenter study. (POPS study).Surgical endoscopy · 2022Article
- Predictors of Incident Serrated Polyps: Results from a Large Multicenter Clinical Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Sessile serrated lesion detection rates during average risk screening colonoscopy: A systematic review and meta-analysis of the published literature.Endoscopy international open · 2021Review
- Evolving Role and Future Directions of Natural Language Processing in Gastroenterology.Digestive diseases and sciences · 2021Review
- Effect of successive endoscopic procedures in polyp and adenoma detection rates: Too early is not always too good.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020Article
- Molecular Biomarkers of Sessile Serrated Adenoma/Polyps.Clinical and translational gastroenterology · 2019Article
- Confounders in Adenoma Detection at Initial Screening Colonoscopy: A Factor in the Assessment of Racial Disparities as a Risk for Colon Cancer.Journal of cancer therapy · 2019Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectivesEndoscopist quality measures such as adenoma detection rate (ADR) and serrated polyp detection rates (SPDRs) depend on pathologist classification of histology. Although variation in pathologic interpretation is recognized, we add to the literature by quantifying the impact of pathologic variability on endoscopist performance.
methodsWe used natural language processing to abstract relevant data from colonoscopy and related pathology reports performed over 2 years at four clinical sites. We quantified each pathologist's likelihood of classifying polyp specimens as adenomas or serrated polyps. We estimated the impact on endoscopists' ADR and SPDR of sending their specimens to pathologists with higher or lower classification rates.
resultsWe observed 85,526 colonoscopies performed by 119 endoscopists; 50,453 had a polyp specimen, which were analyzed by 48 pathologists. There was greater variation across pathologists in classification of serrated polyps than in classification of adenomas. We estimate the endoscopist's average SPDR would be 0.5% if all their specimens were analyzed by the pathologist in our sample with the lowest classification rate and 12.0% if all their specimens were analyzed by the pathologist with the highest classification rate. In contrast, the endoscopist's average ADR would be 28.5% and 42.4% if their specimens were analyzed by the pathologist with lowest and highest classification rate, respectively.
conclusionsThere is significant variation in pathologic interpretation, which more substantially affects endoscopist SPDR than ADR.
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Registered trials
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