Evidence map›Paper›PMID 29380750›Full record

ArticlePhysics in medicine and biology2018

3D prompt gamma imaging for proton beam range verification.

E Draeger, D Mackin, S Peterson, H Chen, S Avery, S Beddar, J C Polf

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 145 citations in OpenAlex.

  1. Article
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  7. Review
  8. 3DPhysics in medicine and biology · 2022
    Article
  9. Review
  10. Compton imaging for medical applications.Radiological physics and technology · 2022
    Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

E DraegerDepartment of Radiation Oncology, University of Maryland School of Medicine, 22 South Greene St., Baltimore, MD 21201, United States of America.
D MackinDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, United States of America.ORCID 0000-0002-2557-5340
S PetersonDepartment of Physics, University of Cape Town, Rondebosch 7700, Cape Town, South Africa.
H ChenDepartment of Radiation Oncology, University of Maryland School of Medicine, 22 South Greene St., Baltimore, MD 21201, United States of America.
S AveryDepartment of Radiation Oncology, University of Pennsylvania, 3400 Civic Center Blvd, Philadelphia, PA 19104, United States of America.
S BeddarDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, United States of America.
J C PolfDepartment of Radiation Oncology, University of Maryland School of Medicine, 22 South Greene St., Baltimore, MD 21201, United States of America.
University of Maryland, Baltimore · US

Funding

Prompt Gamma Imaging for the in-vivo range verification during proton radiotherapyR01CA187416 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI BEDDAR, SAM, KAYE, WILLIAM ROBERT · 2015 to 2019
$2.7M
NCI NIH HHS R01 CA187416
6 · The paper itself

Abstract

We tested the ability of a single Compton camera (CC) to produce 3-dimensional (3D) images of prompt gammas (PGs) emitted during the irradiation of a tissue-equivalent plastic phantom with proton pencil beams for clinical doses delivered at clinical dose rates. PG measurements were made with a small prototype CC placed at three different locations along the proton beam path. We evaluated the ability of the CC to produce images at each location for two clinical scenarios: (1) the delivery of a single 2 Gy pencil beam from a hypo-fractionated treatment (~9  ×  10

Indexed as

Gamma RaysPhantoms, ImagingHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMonte Carlo MethodProton Therapy

Identifiers

PMID29380750
PMCPMC5808927
OpenAlexW2790470968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.