Evidence map›Paper›PMID 29380410›Full record

ArticleJournal of labelled compounds & radiopharmaceuticals2018

Ra-224 labeling of calcium carbonate microparticles for internal α-therapy: Preparation, stability, and biodistribution in mice.

Sara Westrøm, Marion Malenge, Ida Sofie Jorstad, Elisa Napoli, Øyvind S Bruland, Tina B Bønsdorff, Roy H Larsen

Open access · hybridAbstract read
In one paragraph

Article in Journal of labelled compounds & radiopharmaceuticals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 46 citations in OpenAlex.

  1. Normal Tissue Dosimetry of IntraperitonealJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Targeted Radium Alpha Therapy in the Era of Nanomedicine: In Vivo Results.International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Optimized SPECT Imaging ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  10. Article
  11. Article
  12. Intraperitoneal alpha therapy withFrontiers in medicine · 2022
    Article
  13. A Novel Single-Step-LabeledMaterials (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Review
  16. Design and Evaluation ofInternational journal of molecular sciences · 2021
    Article
  17. Improved Formulation ofPharmaceutics · 2021
    Article
  18. Ra-224 activity, half-life, and 241 keV gamma ray absolute emission intensity: A NIST-NPL bilateral comparison.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sara WestrømOncoinvent AS, Oslo, Norway.ORCID 0000-0001-9556-3807
Marion MalengeOncoinvent AS, Oslo, Norway.
Ida Sofie JorstadOncoinvent AS, Oslo, Norway.
Elisa NapoliOncoinvent AS, Oslo, Norway.
Øyvind S BrulandOncoinvent AS, Oslo, Norway.
Tina B BønsdorffOncoinvent AS, Oslo, Norway.
Roy H LarsenOncoinvent AS, Oslo, Norway.
Oncoinvent (Norway) · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Internal therapy with α-emitters should be well suited for micrometastatic disease. Radium-224 emits multiple α-particles through its decay and has a convenient 3.6 days of half-life. Despite its attractive properties, the use of

Indexed as

AnimalsCalcium CarbonateCapsulesMiceRadiopharmaceuticalsRadiotherapyRadiumThoriumTissue DistributionCalcium CarbonateCapsulesRadiopharmaceuticalsRadiumThoriumthorium Xalpha therapycalcium carbonateintraperitonealmicroparticlesperitoneal carcinomatosisradium-224

Identifiers

PMID29380410
PMCPMC6001669
OpenAlexW2793470042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.