Evidence map›Paper›PMID 29380277›Full record

Observational studyJournal of assisted reproduction and genetics2018

First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population.

Frauke von Versen-Höynck, Jenna S Petersen, Yueh-Yun Chi, Jing Liu, Valerie L Baker

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of assisted reproduction and genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Frauke von Versen-HöynckStanford Medicine Fertility and Reproductive Health, Stanford University School of Medicine, 1195 West Fremont Avenue, Suite 1301, Sunnyvale, CA, 94087, USA. frauke@stanford.edu.ORCID http://orcid.org/0000-0002-1924-5695
Jenna S PetersenDepartment of Internal Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA.
Yueh-Yun ChiDepartment of Biostatistics, University of Florida, 2004 Mowry Road, Gainesville, FL, 32611, USA.
Jing LiuDepartment of Biostatistics, University of Florida, 2004 Mowry Road, Gainesville, FL, 32611, USA.
Valerie L BakerStanford Medicine Fertility and Reproductive Health, Stanford University School of Medicine, 1195 West Fremont Avenue, Suite 1301, Sunnyvale, CA, 94087, USA.
University of Florida · USMedizinische Hochschule Hannover · DEOregon Health & Science University · USStanford Medicine · US

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Mechanisms & Consequences of Vascular Adaptations in Pregnancies Conceived by ARTP01HD065647 · NICHD · UNIVERSITY OF FLORIDA · PI CONRAD, KIRK P · 2011 to 2016
$6.1M
Deutsche Forschungsgemeinschaft VE490/8-1National Center for Research Resources UL1 TR001085National Institute of Child Health and Human Development P01 HD065647-01A1NCATS NIH HHS UL1 TR001085
6 · The paper itself

Abstract

purposeThe aim of this study was to determine whether first trimester ultrasound measurements of crown rump length (CRL) and gestational sac diameter (GSD) differ depending on the method of conception among infertile women.

methodInfertile women, ages 21-50 years old, who conceived viable, singleton pregnancies via fresh embryo transfer (ET), frozen ET, non-in vitro fertilization (IVF) fertility treatment, or spontaneously were included in this observational cohort study at an academic fertility practice. Embryonic growth trajectories defined by the CRL and GSD at 6 and 8 weeks' gestation were analyzed and compared among the methods of conception.

resultsCrown rump length at 6 weeks' gestation was smaller for conceptions achieved via fresh ET compared with frozen ET in a natural cycle (1.50 vs. 2.50 mm, p = 0.017). Crown rump length was smaller at 8 weeks' gestation in conceptions achieved via fresh ET compared to frozen ET in a programmed cycle (16.13 vs. 17.02 mm, p = 0.039).

conclusionAmong infertile women, embryo growth may differ between fresh and frozen ET as early as 6 and 8 weeks' gestation.

Indexed as

Crown-Rump LengthAdultCryopreservationEmbryo TransferFemaleFertilizationFertilization in VitroGestational SacHumansInfertility, FemaleInsemination, ArtificialPregnancyPregnancy Trimester, FirstUltrasonography, PrenatalAssisted reproductionCrown rump lengthEmbryo transferFirst trimesterGestational sac diameter

Identifiers

PMID29380277
PMCPMC5984875
OpenAlexW2786780771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.