Evidence map›Paper›PMID 29380155›Full record

ArticleDrug delivery and translational research2018

A coupled bimodal SPECT-CT imaging and brain kinetics studies of zolmitriptan-encapsulated nanostructured polymeric carriers.

Satish K Mandlik, Nisharani S Ranpise, Bhabani S Mohanty, Pradip R Chaudhari

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Review
  7. Imaging of intranasal drug delivery to the brain.American journal of nuclear medicine and molecular imaging · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Satish K MandlikDepartment of Pharmaceutics, Sinhgad Technical Education Society's, Sinhgad College of Pharmacy, Vadgaon (Bk.), Pune, Maharashtra, India. satish4004@gmail.com.
Nisharani S RanpiseDepartment of Pharmaceutics, Sinhgad Technical Education Society's, Sinhgad College of Pharmacy, Vadgaon (Bk.), Pune, Maharashtra, India.
Bhabani S MohantySmall Animal Imaging Facility, ACTREC, Navi Mumbai, Maharashtra, India.
Pradip R ChaudhariSmall Animal Imaging Facility, ACTREC, Navi Mumbai, Maharashtra, India.
Advanced Centre for Treatment, Research and Education in Cancer · INSinhgad Dental College and Hospital · IN

Funding

Savitribai Phule Pune University, Pune , India 13PHM000486
6 · The paper itself

Abstract

The present investigation deals with preparation and characterization of anti-migraine zolmitriptan (ZMT) nanostructured polymeric carriers for nose to brain drug targeting. The drug-loaded colloidal nanocarriers of ZMT were prepared by modified ionic gelation of cationic chitosan with anionic sodium tripolyphosphate and characterized for particle size, zeta potential, and entrapment efficiency. Further, in order to investigate nose to brain drug targeting, biodistribution, and brain kinetics studies were performed using

Indexed as

Administration, IntranasalAdministration, IntravenousAnimalsBrainChitosanDrug CarriersKineticsMaleMiceNanostructuresOxazolidinonesPolyphosphatesSerotonin 5-HT1 Receptor AgonistsTechnetiumTissue DistributionTomography, Emission-Computed, Single-PhotonChitosanDrug CarriersOxazolidinonesPolyphosphatesSerotonin 5-HT1 Receptor AgonistsTechnetiumtriphosphoric acidTryptamineszolmitriptanBrain kineticsBrain targetingNanostructured polymeric carriersSPECT-CT

Identifiers

PMID29380155
OpenAlexW2793993550

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.