Observational studyJAMA internal medicine2018
Prevalence of Pulmonary Embolism in Patients With Syncope.
Observational study in JAMA internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Exercise and pulmonary embolism: a systematic review of exercise safety, feasibility and effectiveness.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Syncope Time Frames for Adverse Events after Emergency Department Presentation: An Individual Patient Data Meta-Analysis.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Factors influencing harmonized health data collection, sharing and linkage in Denmark and Switzerland: A systematic review.PloS one · 2019Pooled it
- Diagnostic Validation of PERC and Resource Utilization in Suspected Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Syncope and In-Hospital Mortality in Pulmonary Embolism: Insights from 300 Patients.Life (Basel, Switzerland) · 2025Article
- Syncope as the Initial Presentation of Severe Pulmonary Embolism Without Hypoxemia: A Clinical Case.Cureus · 2025Article
- Trends in syncope testing and admissions in the USA from 2006 through 2019.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025Article
- Syncope in the Emergency Department: A Practical Approach.Journal of clinical medicine · 2024Review
- Intermediate-Risk and High-Risk Pulmonary Embolism: Recognition and Management: Cardiology Clinics: Cardiac Emergencies.Cardiology clinics · 2024Review
- "Hospital survival of patients with pulmonary embolism in a country with limited resources case of the city of Kinshasa".BMC cardiovascular disorders · 2023Article
- Case report: An elderly woman with recurrent syncope after pacemaker implantation.Frontiers in cardiovascular medicine · 2023Article
- Article
- Choosing Wisely in clinical practice: Embracing critical thinking, striving for safer care.Journal of internal medicine · 2022Review
- Prevalence of venous thromboembolism in admissions and readmissions with and without syncope: a nationwide cohort study.European heart journal. Quality of care & clinical outcomes · 2021Observational
- [Syncope in pulmonary embolism].Der Internist · 2021Article
- D-Dimer Tests in the Emergency Department: Current Insights.Open access emergency medicine : OAEM · 2021Review
- Article
- Diagnostic yield of pulmonary embolism testing in patients presenting to the emergency department with syncope.Research and practice in thrombosis and haemostasis · 2020Article
- Opportunistic Diagnosis of Extensive Pulmonary Embolus Following "COVID-19 Blood Battery" in Very Frail Older Patients.The journal of nutrition, health & aging · 2020Article
- Thirty-day readmissions due to Venous thromboembolism in patients discharged with syncope.PloS one · 2020Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Importance: Sparse data and conflicting evidence exist on the prevalence of pulmonary embolism (PE) in patients with syncope. Objective: To estimate the prevalence of PE among patients presenting to the emergency department (ED) for evaluation of syncope. Design, Setting, and Participants: This retrospective, observational study analyzed longitudinal administrative data from 5 databases in 4 different countries (Canada, Denmark, Italy, and the United States). Data from all adult patients (aged ≥18 years) who presented to the ED were screened to identify those with syncope codes at discharge. Data were collected from January 1, 2000, through September 30, 2016. Main Outcomes and Measures: The prevalence of PE at ED and hospital discharge, identified using codes from the International Classification of Diseases, was considered the primary outcome. Two sensitivity analyses considering prevalence of PE at 90 days of follow-up and prevalence of venous thromboembolism were performed. Results: A total of 1 671 944 unselected adults who presented to the ED for syncope were included. The prevalence of PE, according to administrative data, ranged from 0.06% (95% CI, 0.05%-0.06%) to 0.55% (95% CI, 0.50%-0.61%) for all patients and from 0.15% (95% CI, 0.14%-0.16%) to 2.10% (95% CI, 1.84%-2.39%) for hospitalized patients. The prevalence of PE at 90 days of follow-up ranged from 0.14% (95% CI, 0.13%-0.14%) to 0.83% (95% CI, 0.80%-0.86%) for all patients and from 0.35% (95% CI, 0.34%-0.37%) to 2.63% (95% CI, 2.34%-2.95%) for hospitalized patients. Finally, the prevalence of venous thromboembolism at 90 days ranged from 0.30% (95% CI, 0.29%-0.31%) to 1.37% (95% CI, 1.33%-1.41%) for all patients and from 0.75% (95% CI, 0.73%-0.78%) to 3.86% (95% CI, 3.51%-4.24%) for hospitalized patients. Conclusions and Relevance: Pulmonary embolism was rarely identified in patients with syncope. Although PE should be considered in every patient, not all patients should undergo evaluation for PE.
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