Evidence map›Paper›PMID 29379895›Full record

ArticleJournal of the Endocrine Society2018

Aberrant Iodine Autoregulation Induces Hypothyroidism in a Mouse Strain in the Absence of Thyroid Autoimmunity.

Sandra M McLachlan, Holly A Aliesky, Basil Rapoport

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Low Dietary Iodine Intake and Sex-Specific Mortality in Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sandra M McLachlanThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute, Los Angeles, California 90048.
Holly A AlieskyThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute, Los Angeles, California 90048.
Basil RapoportThyroid Autoimmune Disease Unit, Cedars-Sinai Research Institute, Los Angeles, California 90048.
Cedars-Sinai Medical Center · US

Funding

MODULATION OF AN ANIMAL MODEL OF HYPERTHYROIDISMR01DK054684 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI MCLACHLAN, SANDRA M · 1999 to 2017
$5.6M
NIDDK NIH HHS R01 DK054684
6 · The paper itself

Abstract

We investigated factors underlying the varying effects of a high dietary iodide intake on serum T4 levels in a wide spectrum of mouse strains, including thyroiditis-susceptible NOD.H2

Indexed as

hypothyroidismiodide-symporteriodine autoregulationTSH

Identifiers

PMID29379895
PMCPMC5779109
OpenAlexW2775219024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.