Evidence map›Paper›PMID 29379786›Full record

ArticleFrontiers in surgery2017

Posterior Tracheopexy for Severe Tracheomalacia Associated with Esophageal Atresia (EA): Primary Treatment at the Time of Initial EA Repair versus Secondary Treatment.

Hester F Shieh, C Jason Smithers, Thomas E Hamilton, David Zurakowski, Gary A Visner, Michael A Manfredi, Christopher W Baird, Russell W Jennings

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06335862 (Primary pOsterioR TRacheopexy Prevents Collapse of the Trachea in Newborns With Oesophageal AtresIa and Tracheomalacia), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06335862 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Primary pOsterioR TRacheopexy Prevents Collapse of the Trachea in Newborns With Oesophageal AtresIa and Tracheomalacia

TypeinterventionalSponsorUMC UtrechtRan2024 to 2027Enrolled78ConditionsOesophageal Atresia With Tracheo-Oesophageal Fistula, Tracheomalacia, Oesophageal AtresiaArmsRandomisation between the PPT- and no-PPT-group, Primary Posterior Tracheopexy, Preoperative tracheobronchoscopy, Intraoperative tracheobronchoscopy, Postoperative tracheobronchoscopy through the endotracheal tube during extubation
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Tracheomalacia and surgical options: A case series perspective.Acta paediatrica (Oslo, Norway : 1992) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Imaging in neonatal respiratory disease.Paediatric respiratory reviews · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hester F ShiehDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
C Jason SmithersDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Thomas E HamiltonDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
David ZurakowskiDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Gary A VisnerDepartment of Pulmonology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Michael A ManfrediDepartment of Gastroenterology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Christopher W BairdDepartment of Cardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Russell W JenningsDepartment of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Boston Children's Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe review outcomes of posterior tracheopexy for tracheomalacia in esophageal atresia (EA) patients, comparing primary treatment at the time of initial EA repair versus secondary treatment.

methodsAll EA patients who underwent posterior tracheopexy from October 2012 to September 2016 were retrospectively reviewed. Clinical symptoms, tracheomalacia scores, and persistent airway intrusion were collected. Indication for posterior tracheopexy was the presence of clinical symptoms, in combination with severe tracheomalacia as identified on bronchoscopic evaluation, typically defined as coaptation in one or more regions of the trachea. Secondary cases were usually those with chronic respiratory symptoms who underwent bronchoscopic evaluation, whereas primary cases were those found to have severe tracheomalacia on routine preoperative dynamic tracheobronchoscopy at the time of initial EA repair.

resultsA total of 118 patients underwent posterior tracheopexy: 18 (15%) primary versus 100 (85%) secondary cases. Median (interquartile range) age was 2 months (1-4 months) for primary (22% type C) and 18 months (8-40 months) for secondary (87% type C) cases (

conclusionPosterior tracheopexy is effective in treating severe tracheomalacia with significant improvements in clinical symptoms and degree of airway collapse on bronchoscopy. With no significant differences in outcomes between primary and secondary treatment, posterior tracheopexy should be selectively considered at the time of initial EA repair.

Indexed as

airway collapsebrief resolved unexplained eventsesophageal atresiaposterior tracheopexytracheomalacia

Identifiers

PMID29379786
PMCPMC5775263
OpenAlexW2784297581

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.