Evidence map›Paper›PMID 29379636›Full record

ArticleFuture science OA2018

Could IGF-I levels play a neuroprotective role in patients with large vestibular schwannomas?

George Fotakopoulos, Kostas Fountas, Eleni Tsianaka, Polikceni Kotlia, Dimitrios Pachatouridis, Thanos Paschalis, Spyridon Voulgaris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future science OA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. A Review of Drug Therapy in Vestibular Schwannoma.Drug design, development and therapy · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

George FotakopoulosDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
Kostas FountasDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
Eleni TsianakaDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
Polikceni KotliaDepartment of Head of Critical Care, University of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
Dimitrios PachatouridisDepartment of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece.
Thanos PaschalisDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
Spyridon VoulgarisDepartment of Neurosurgery, University Hospital of Ioannina, Ioannina, Greece.
University Hospital of Larissa · GRUniversity Hospital of Ioannina · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the possible superiority of outcome in patients with elevated IGF-I levels after vestibular schwannoma (VS) resection. PATIENTS &

methodsThis retrospective study included 65 patients (34 male, 52.3%) with VS operated in between January 2009 and April 2014 (follow-up 3.2 ± 0.7 years). Preoperative or postoperative IGF-I levels were identified for each patient.

resultsPatients were divided into two groups: Group A (small size tumor), 56 patients; and Group B (large size tumor), 9 cases. IGF-I levels in Group A (195.8 ± 32.9 ng/ml) were compared with those of Group B (242.2 ± 22.2 ng/ml) and were found to have statistically significant difference (p = 0.001).

conclusionIncreased IGF-I levels could hold a key role in nerve recovery in patients undergoing surgical resection of large VS.

Indexed as

IGF-Ineuroprotectionvestibular schwannoma

Identifiers

PMID29379636
PMCPMC5778376
OpenAlexW2767708198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.