Trial reportOxidative medicine and cellular longevity2017
Low-Level Laser Irradiation Exerts Antiaggregative Effect on Human Platelets Independently on the Nitric Oxide Metabolism and Release of Platelet Activation Markers.
Trial report in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Comparison of platelet-rich plasma efficacy with and without photoactivation in melasma: A randomized double-blind study.Journal of cosmetic dermatology · 2024Trial
- Effect of In Vitro Low-Impulse Laser Irradiation on Morphofunctional Properties of Human Platelets.Bulletin of experimental biology and medicine · 2024Article
- X-rays Stimulate Granular Secretions and Activate Protein Kinase C Signaling in Human Platelets.Current issues in molecular biology · 2023Article
- Near-infrared photobiomodulation of blood reversibly inhibits platelet reactivity and reduces hemolysis.Scientific reports · 2022Article
- Light-based technologies for management of COVID-19 pandemic crisis.Journal of photochemistry and photobiology. B, Biology · 2020Review
- Article
- Therapeutic potential of intranasal photobiomodulation therapy for neurological and neuropsychiatric disorders: a narrative review.Reviews in the neurosciences · 2020Review
- Low-Level Light Therapy Protects Red Blood Cells Against Oxidative Stress and Hemolysis During Extracorporeal Circulation.Frontiers in physiology · 2018Article
- Corrigendum to "Low-Level Laser Irradiation Exerts Antiaggregative Effect on Human Platelets Independently on the Nitric Oxide Metabolism and Release of Platelet Activation Markers".Oxidative medicine and cellular longevity · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe goal of the study is to develop a model allowing to investigate precisely the effect of low-level laser therapy (LLLT) on platelet aggregation and to verify the hypothesis regarding the role of the nitric oxide (NO) bioavailability and platelet activation markers in modulating platelet aggregation.
methodsA total of 41 healthy volunteers at the age of 21-45 years were investigated. At first, platelet aggregation in response to three agonists (TRAP, ADP, and collagen) was evaluated following previous exposure to different doses of laser radiation (
resultsAll doses of laser irradiation significantly reduced the aggregation. However, the most pronounced effect was observed for 19.7 J/cm
conclusionsWe have demonstrated in the established
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.