Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant.

Sumeyra Dogan, Mehmet S Dogan, Filiz Tutunculer, Ozge Yapiciugurlar, Hakan Genchellac

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In one paragraph

Article in Iranian journal of child neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 99% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Neurochemical Anatomy of Cushing's Syndrome.Neurochemical research · 2024
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sumeyra DoganDepartment of Pediatric Radiology, Trakya University, Faculty of Medicine, Edirne, Turkey.

Mehmet S DoganDepartment of Pediatric Radiology, Trakya University, Faculty of Medicine, Edirne, Turkey.

Filiz TutunculerDepartment of Pediatric Endocrinology, Faculty of Medicine, Trakya University, Edirne, Turkey.

Ozge YapiciugurlarDepartment of Pediatric Radiology, Trakya University, Faculty of Medicine, Edirne, Turkey.

Hakan GenchellacDepartment of Pediatric Radiology, Trakya University, Faculty of Medicine, Edirne, Turkey.

Trakya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.

Indexed as

Brain atrophyDiaper dermatitisIatrogenic Cushing’s syndromeMagnetic resonance imagingMyelination

Identifiers

PMID29379569

PMCPMC5760680

OpenAlexW2788140702

What OpenQuestion holds

Textmetadata

LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.