Evidence map›Paper›PMID 29379552›Full record

ArticleArchives of medical science : AMS2018

Differential action of polyunsaturated fatty acids and eicosanoids on bleomycin-induced cytotoxicity to neuroblastoma cells and lymphocytes.

Sailaja Polavarapu, Bilikere S Dwarakanath, Undurti N Das

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. AA and Parkinson's Disease.Reviews of physiology, biochemistry and pharmacology · 2027
    Review
  2. AA-Induced Lipid Peroxidation at the Center of Tumor Cell Apoptosis and Ferroptosis.Reviews of physiology, biochemistry and pharmacology · 2027
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sailaja PolavarapuBioScience Research Centre, Gayatri Vidya Parishad College of Engineering Campus, Madhurawada, Andhra Pradesh, India.
Bilikere S DwarakanathInstitute of Nuclear Medicine and Allied Sciences, DRDO, New Delhi, India.
Undurti N DasBioScience Research Centre, Gayatri Vidya Parishad College of Engineering Campus, Madhurawada, Andhra Pradesh, India.
Institute of Nuclear Medicine & Allied Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study was conducted to examine whether bleomycin-induced growth inhibitory action on human neuroblastoma cells (IMR-32) is influenced by anti-inflammatory metabolites of polyunsaturated fatty acids (PUFAs): lipoxin A4 (LXA4), resolvin D1 and protectin D1 MATERIAL AND

methodsThe

resultsPUFAs inhibited the growth of IMR-32 cells (EPA > DHA = AA > GLA = ALA > DGLA = LA) significantly (

conclusionsBioactive lipids have differential action on normal human lymphocytes and tumor cells

Indexed as

bleomycincytotoxicitylipoxin A4lymphocytesneuroblastomapolyunsaturated fatty acidsprostaglandinsprotectinresolvin

Identifiers

PMID29379552
PMCPMC5778433
OpenAlexW2781652101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.