Evidence map›Paper›PMID 29379485›Full record

ReviewFrontiers in microbiology2017

Endogenous Retrovirus 3 - History, Physiology, and Pathology.

Yomara Y Bustamante Rivera, Christine Brütting, Caroline Schmidt, Ines Volkmer, Martin S Staege

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  8. Type I interferon activation and endothelial dysfunction in caveolin-1 insufficiency-associated pulmonary arterial hypertension.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yomara Y Bustamante RiveraDepartment of Paediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.
Christine BrüttingDepartment of Paediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.
Caroline SchmidtDepartment of Paediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.
Ines VolkmerDepartment of Paediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.
Martin S StaegeDepartment of Paediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous viral elements (EVE) seem to be present in all eukaryotic genomes. The composition of EVE varies between different species. The endogenous retrovirus 3 (ERV3) is one of these elements that is present only in humans and other Catarrhini. Conservation of ERV3 in most of the investigated Catarrhini and the expression pattern in normal tissues suggest a putative physiological role of ERV3. On the other hand, ERV3 has been implicated in the pathogenesis of auto-immunity and cancer. In the present review we summarize knowledge about this interesting EVE. We propose the model that expression of ERV3 (and probably other EVE loci) under pathological conditions might be part of a metazoan SOS response.

Indexed as

autoimmunitycancerendogenous retrovirusesendogenous viral elementsERV3SOS responseultra-stabilityZNF117

Identifiers

PMID29379485
PMCPMC5775217
OpenAlexW2783347513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.