ArticleFrontiers in neurology2017
Health-Related Quality of Life Is Severely Affected in Primary Orthostatic Tremor.
Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Treatment Continuation and Long-Term Outcomes of Perampanel in Primary Orthostatic Tremor; A Cohort Study.Movement disorders clinical practice · 2026Observational
- Orthostatic tremor and its subtypes: a single centre cohort of 74 patients.Journal of neurology · 2026Article
- Clinical Characteristics of Primary Orthostatic Tremor - a Comprehensive Clinical Assessment of Patients in Sweden.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Identifying the Diagnostic Challenges and Indicators of Orthostatic Tremor: Patient Perspectives.Movement disorders clinical practice · 2025Article
- Usability, safety and tolerability of CUE1 vibrotactile device as promising therapeutic approach in orthostatic tremor.Clinical parkinsonism & related disorders · 2025Article
- Effect of Orthostatic Tremor on Quality of Life - a Cohort Study.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Deep Brain Stimulation for Orthostatic Tremor: An Observational Study.Movement disorders clinical practice · 2024Observational
- Primary orthostatic tremor and orthostatic tremor-plus in dogs: 60 cases (2003-2020).Journal of veterinary internal medicine · 2022Article
- Diagnosis of orthostatic tremor using smartphone accelerometry.BMC neurology · 2021Article
- The Top 50 Most-Cited Articles in Orthostatic Tremor: A Bibliometric Review.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019Review
- The use of smartphone in measuring stance and gait patterns in patients with orthostatic tremor.PloS one · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 11 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary orthostatic tremor (POT) is a movement disorder characterized by unsteadiness upon standing still due to a tremor affecting the legs. It is a gradually progressive condition with limited treatment options. Impairments in health-related quality of life (HQoL) seem to far exceed the physical disability associated with the condition.
methodsA multi-center, mixed-methodology study was undertaken to investigate 40 consecutive patients presenting with POT to four movement disorder centers in France. HQoL was investigated using eight quantitative scales and a qualitative study which employed semi-structured interviews. Qualitative data were analyzed with a combination of grounded-theory approach.
resultsOur results confirm that HQoL in POT is severely affected. Fear of falling was identified as the main predictor of HQoL. The qualitative arm of our study explored our initial results in greater depth and uncovered themes not identified by the quantitative approach.
conclusionOur results illustrate the huge potential of mixed methodology in identifying issues influencing HQoL in POT. Our work paves the way for enhanced patient care and improved HQoL in POT and is paradigmatic of this modern approach for investigating HQoL issues in chronic neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.