Evidence map›Paper›PMID 29379421›Full record

ArticleFrontiers in systems neuroscience2017

Octopamine and Tyramine Contribute Separately to the Counter-Regulatory Response to Sugar Deficit in

Christine Damrau, Naoko Toshima, Teiichi Tanimura, Björn Brembs, Julien Colomb

Open access · goldAbstract read
In one paragraph

Article in Frontiers in systems neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Octopamine receptors inFrontiers in molecular neuroscience · 2026
    Article
  4. Hunger Recruits a Parallel Circuit Encoding Alcohol Reward.bioRxiv : the preprint server for biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Christine DamrauNeurobiologie, Fachbereich Biologie-Chemie-Pharmazie, Institut für Biologie - Neurobiologie, Freie Universität Berlin, Berlin, Germany.
Naoko ToshimaDivision of Biological Sciences, Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan.
Teiichi TanimuraDivision of Biological Sciences, Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan.
Björn BrembsNeurobiologie, Fachbereich Biologie-Chemie-Pharmazie, Institut für Biologie - Neurobiologie, Freie Universität Berlin, Berlin, Germany.
Julien ColombNeurobiologie, Fachbereich Biologie-Chemie-Pharmazie, Institut für Biologie - Neurobiologie, Freie Universität Berlin, Berlin, Germany.
Freie Universität Berlin · DEKyushu University · JPUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All animals constantly negotiate external with internal demands before and during action selection. Energy homeostasis is a major internal factor biasing action selection. For instance, in addition to physiologically regulating carbohydrate mobilization, starvation-induced sugar shortage also biases action selection toward food-seeking and food consumption behaviors (the counter-regulatory response). Biogenic amines are often involved when such widespread behavioral biases need to be orchestrated. In mammals, norepinephrine (noradrenalin) is involved in the counterregulatory response to starvation-induced drops in glucose levels. The invertebrate homolog of noradrenalin, octopamine (OA) and its precursor tyramine (TA) are neuromodulators operating in many different neuronal and physiological processes. Tyrosine-ß-hydroxylase (

Indexed as

biogenic aminesinsectsproboscis extension responsestarvationstarvation resistance

Identifiers

PMID29379421
PMCPMC5775261
OpenAlexW2784064212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.