Evidence map›Paper›PMID 29379412›Full record

ArticleFrontiers in neuroscience2017

Functional Characterization and Signaling Systems of Corazonin and Red Pigment Concentrating Hormone in the Green Shore Crab,

Jodi L Alexander, Andrew Oliphant, David C Wilcockson, Neil Audsley, Rachel E Down, Rene Lafont, Simon G Webster

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

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  8. Insects as a New Complex Model in Hormonal Basis of Obesity.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Jodi L AlexanderSchool of Biological Sciences, Brambell Laboratories, Bangor University, Bangor, United Kingdom.
Andrew OliphantInstitute of Biological Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom.
David C WilcocksonInstitute of Biological Environmental and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom.
Neil AudsleyFera Science Ltd, York, United Kingdom.
Rachel E DownFera Science Ltd, York, United Kingdom.
Rene LafontIBPS-BIOSIPE, Sorbonne Universités, UPMC Univ Paris 06, Paris, France.
Simon G WebsterSchool of Biological Sciences, Brambell Laboratories, Bangor University, Bangor, United Kingdom.
Bangor University · GBFera Science (United Kingdom) · GBAberystwyth University · GBInstitute of Biological, Environmental and Rural Sciences · GBSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropeptides play a central role as neurotransmitters, neuromodulators and hormones in orchestrating arthropod physiology. The post-genomic surge in identified neuropeptides and their putative receptors has not been matched by functional characterization of ligand-receptor pairs. Indeed, until very recently no G protein-coupled receptors (GPCRs) had been functionally defined in any crustacean. Here we explore the structurally-related, functionally-diverse gonadotropin-releasing hormone paralogs, corazonin (CRZ) and red-pigment concentrating hormone (RPCH) and their G-protein coupled receptors (GPCRs) in the crab,

Indexed as

Carcinus maenascorazoninG protein-coupled receptorsmRNA and peptide expressionneuroanatomyneuropeptidesphysiological rolesred pigment concentrating hormone

Identifiers

PMID29379412
PMCPMC5775280
OpenAlexW2784200411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.