Evidence map›Paper›PMID 29379280›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2018

Airway reactivity to mannitol is similarly increased in chronic cigarette and water pipe smokers.

Andreas Scherr, Jerome Schmidlin, Silvio Albisser, Michael Tamm, Daiana Stolz

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andreas ScherrClinic for Pneumology and Respiratory Cell Research, University Hospital of Basel, Basel, Switzerland.
Jerome SchmidlinClinic for Pneumology and Respiratory Cell Research, University Hospital of Basel, Basel, Switzerland.
Silvio AlbisserClinic for Pneumology and Respiratory Cell Research, University Hospital of Basel, Basel, Switzerland.
Michael TammClinic for Pneumology and Respiratory Cell Research, University Hospital of Basel, Basel, Switzerland.
Daiana StolzClinic for Pneumology and Respiratory Cell Research, University Hospital of Basel, Basel, Switzerland.
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In contrast to cigarette smoking, the association between water pipe smoking and airway hyperresponsiveness remains widely unexplored. Methods: A bronchoprovocation challenge with mannitol was performed in young adults recruited at the University of Basel, Switzerland. Subjects were categorized as acute water pipe smokers (single episode of water pipe smoking, no or <0.5 pack-years cigarette smoking); chronic water pipe smokers (weekly for ≥4 weeks, no or <0.5 pack-years cigarette smoking); cigarette smokers (no water pipe smokers); and never-smokers (no cigarette or water pipe smokers). Primary outcomes were airway reactivity as measured by the response-to-dose ratio (RDR) and airway responsiveness measured by the provocation dose to cause a 15% fall in forced expiratory volume in 1s (FEV Results: Seventy-four subjects with a mean age of 22.5±2.5 years and FEV Conclusion: Weekly water pipe smoking may increase airway reactivity to a similar extent as cigarette smoking.

Indexed as

Bronchial Provocation TestsBronchoconstrictionAdolescentAdultBronchial HyperreactivityBronchoconstrictor AgentsCigarette SmokingFemaleForced Expiratory VolumeHumansLungMaleMannitolPredictive Value of TestsProspective StudiesSmokingBronchoconstrictor AgentsMannitolairway reactivitymannitol challengewater pipe smoking

Identifiers

PMID29379280
PMCPMC5757204
OpenAlexW2781705290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.