Evidence map›Paper›PMID 29379194›Full record

ArticleEuropean journal of human genetics : EJHG2018

Psychosocial impact on mothers receiving expanded newborn screening results.

Kathleen O'Connor, Tara Jukes, Sharan Goobie, Jennifer DiRaimo, Greg Moran, Beth Katherine Potter, Pranesh Chakraborty, Charles Anthony Rupar, Srinitya Gannavarapu, Chitra Prasad

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of human genetics : EJHG, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Article
  8. Article
  9. Article
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  11. Review
  12. Communicating a Positive Result at Newborn Screening and Parental Distress.International journal of neonatal screening · 2023
    Article
  13. Review
  14. Article
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  16. Article
  17. Review
  18. "EClinicalMedicine · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kathleen O'ConnorDepartment of Psychology, Western University, London, ON, Canada.
Tara JukesDepartment of Psychology, Western University, London, ON, Canada.
Sharan GoobieDepartment of Pediatrics, Western University, London, ON, Canada.
Jennifer DiRaimoDepartment of Pediatrics, Western University, London, ON, Canada.
Greg MoranDepartment of Psychology, Western University, London, ON, Canada.
Beth Katherine PotterSchool of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, ON, Canada.
Pranesh ChakrabortyNewborn Screening, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Charles Anthony RuparDepartment of Pediatrics, Western University, London, ON, Canada.
Srinitya GannavarapuDepartment of Pediatrics, Western University, London, ON, Canada.
Chitra PrasadDepartment of Pediatrics, Western University, London, ON, Canada. chitra.prasad@lhsc.on.ca.
Western University · CAChildren’s Health Research Institute · CAChildren's Hospital of Eastern Ontario · CAUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expanded newborn screening (NBS) for genetic disorders has improved diagnosis of numerous treatable diseases, positively impacting children's health outcomes. However, research about the psychological impact of expanded NBS on families, especially mothers, has been mixed. Our study examined associations between maternal experiences of expanded NBS and subsequent psychosocial functioning and parenting stress in mothers whose infants received either true negative (TN), true positive (TP) or false positive (FP) results after a 4- to 6-month period. The Parenting Stress Index and the Depression, Anxiety and Stress Scale were used to assess symptoms of anxiety, stress and depression in 3 sets of mothers, whose infants received TN (n = 31), TP (n = 8) or FP (n = 18) results. Multivariate analyses of variance (MANOVA) results revealed no significant differences among these three groups of mothers regarding overall anxiety, stress and depression. However, FP mothers experienced lower levels of stress related to their own health compared to TN group. Two potential trends were also identified; results suggested TN mothers might experience higher levels of isolation than mothers in the TP group and that FP mothers might report higher stress levels in relation to spousal relationships compared to the TN group. FP mothers seemed to report similar or better levels of psychosocial functioning than TN mothers. Our findings are encouraging with respect to impacts of NBS on maternal well-being. We also identify key areas for improvement (parental education) and research (isolation and spousal relationships).

Indexed as

AdultFemaleGenetic CounselingGenetic TestingHumansInfant, NewbornMetabolism, Inborn ErrorsMothersNeonatal ScreeningStress, Psychological

Identifiers

PMID29379194
PMCPMC5891497
OpenAlexW2791424135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.