ArticleScientific reports2018
Foxj1 expressing ependymal cells do not contribute new cells to sites of injury or stroke in the mouse forebrain.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Ependymal and neural stem cells are close relatives.Stem cell reports · 2025Review
- Blueprints for healing: central nervous system regeneration in zebrafish and neonatal mice.BMC biology · 2025Review
- Characterizing progenitor cells in developing and injured spinal cord: Insights from single-nucleus transcriptomics and lineage tracing.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Role of Oligodendrocyte Lineage Cells in White Matter Injury.Advances in neurobiology · 2025Review
- Multiciliated ependymal cells: an update on biology and pathology in the adult brain.Acta neuropathologica · 2024Review
- Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.Nature neuroscience · 2024Article
- Heterozygous FOXJ1 Mutations Cause Incomplete Ependymal Cell Differentiation and Communicating Hydrocephalus.Cellular and molecular neurobiology · 2023Article
- In vivo cell fate reprogramming for spinal cord repair.Current opinion in genetics & development · 2023Review
- The activation of dormant ependymal cells following spinal cord injury.Stem cell research & therapy · 2023Review
- Roles of Ependymal Cells in the Physiology and Pathology of the Central Nervous System.Aging and disease · 2023Review
- Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish.Cell reports · 2022Article
- DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential.Developmental cell · 2022Article
- Lineage tracing reveals the origin of Nestin-positive cells are heterogeneous and rarely from ependymal cells after spinal cord injury.Science China. Life sciences · 2022Article
- Review
- Single-cell RNA sequencing reveals NestinScience China. Life sciences · 2022Article
- In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury.Cell stem cell · 2021Article
- Genetic targeting of neurogenic precursors in the adult forebrain ventricular epithelium.Life science alliance · 2020Article
- Regeneration ThroughFrontiers in cellular neuroscience · 2020Review
- Functions of subventricular zone neural precursor cells in stroke recovery.Behavioural brain research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The stem cell source of neural and glial progenitors in the periventricular regions of the adult forebrain has remained uncertain and controversial. Using a cell specific genetic approach we rule out Foxj1+ ependymal cells as stem cells participating in neurogenesis and gliogenesis in response to acute injury or stroke in the mouse forebrain. Non stem- and progenitor-like responses of Foxj1+ ependymal cells to injury and stroke remain to be defined and investigated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.