Evidence map›Paper›PMID 29379020›Full record

ArticleNature communications2018

Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.

Baixing Wu, Shichen Su, Deepak P Patil, Hehua Liu, Jianhua Gan, Samie R Jaffrey, Jinbiao Ma

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 285 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
285citing papers in PubMed, 1 pooled it
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

285 citing papers in PubMed, 1 synthesis or guideline pooled it, 395 citations in OpenAlex.

  1. RNA methylation in vascular disease: a systematic review.Journal of cardiothoracic surgery · 2022
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. SuppressedInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Methylation marks breast cancer metastasis: The roles of mThe Journal of biological chemistry · 2026
    Review
  13. Review
  14. RBM45 Preferential Binding to mThe journal of physical chemistry. B · 2026
    Article
  15. Article
  16. Article
  17. Regulation of mCell biology and toxicology · 2026
    Review
  18. Article
  19. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  20. Review

225 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Baixing WuState Key Laboratory of Genetic Engineering, Collaborative Innovation Centre of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Shichen SuState Key Laboratory of Genetic Engineering, Collaborative Innovation Centre of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Deepak P PatilDepartment of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY, 10065, USA.
Hehua LiuState Key Laboratory of Genetic Engineering, Collaborative Innovation Centre of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Jianhua GanState Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Physiology and Biophysics, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Samie R JaffreyDepartment of Pharmacology, Weill Cornell Medicine, Cornell University, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0003-3615-6958
Jinbiao MaState Key Laboratory of Genetic Engineering, Collaborative Innovation Centre of Genetics and Development, Department of Biochemistry, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai, 200438, China. majb@fudan.edu.cn.ORCID http://orcid.org/0000-0002-0232-1786
Fudan University · CNCornell University · US

Funding

Mechanisms of epitranscriptomic regulation in cancerR01CA186702 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAMIE R JAFFREY, Michael Kharas · 2014 to 2026
$8.0M
NCI NIH HHS R01 CA186702
6 · The paper itself

Abstract

Human hnRNP A2/B1 is an RNA-binding protein that plays important roles in many biological processes, including maturation, transport, and metabolism of mRNA, and gene regulation of long noncoding RNAs. hnRNP A2/B1 was reported to control the microRNAs sorting to exosomes and promote primary microRNA processing as a potential m

Indexed as

RNA Recognition MotifHeterogeneous-Nuclear Ribonucleoprotein Group A-BHumansRNAHeterogeneous-Nuclear Ribonucleoprotein Group A-BhnRNP A2RNA

Identifiers

PMID29379020
PMCPMC5789076
OpenAlexW2620642044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.