Evidence map›Paper›PMID 29378891›Full record

ArticleJournal of bacteriology2018

Nutritional Regulation of the Sae Two-Component System by CodY in Staphylococcus aureus.

Kevin D Mlynek, William E Sause, Derek E Moormeier, Marat R Sadykov, Kurt R Hill, Victor J Torres, Kenneth W Bayles, Shaun R Brinsmade

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 43 citations in OpenAlex.

  1. InJournal of bacteriology · 2026
    Article
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  4. InbioRxiv : the preprint server for biology · 2026
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  8. mBio · 2025
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  9. bioRxiv : the preprint server for biology · 2025
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  10. Article
  11. Article
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  13. Integrated genomic and proteomic analysis of the mouse-adaptedCurrent research in microbial sciences · 2025
    Article
  14. Article
  15. ThebioRxiv : the preprint server for biology · 2024
    Article
  16. Loratadine Combats Methicillin-ResistantACS infectious diseases · 2024
    Article
  17. Article
  18. Review
  19. A Review of Biofilm Formation ofAntibiotics (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kevin D MlynekDepartment of Biology, Georgetown University, Washington, DC, USA.
William E SauseDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Derek E MoormeierDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Marat R SadykovDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Kurt R HillDepartment of Biology, Georgetown University, Washington, DC, USA.
Victor J TorresDepartment of Microbiology, New York University School of Medicine, New York, New York, USA.
Kenneth W BaylesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Shaun R BrinsmadeDepartment of Biology, Georgetown University, Washington, DC, USA shaun.brinsmade@georgetown.edu.ORCID https://orcid.org/0000-0002-5381-2817
Georgetown University · USUniversity of Nebraska Medical Center · USNew York University · US

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI HANDKE, LUKE D · 2009 to 2023
$32.1M
INFECTIOUS DISEASES &BASIC MICROBIOLOGICAL MECHANISMST32AI007180 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEISER, JEFFREY NEAL · 1985 to 2022
$8.9M
Mechanistic Studies Of The Staphylococcus aureus LukAB CytotoxinR01AI099394 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Victor J. Torres · 2013 to 2026
$6.1M
Contribution of LukED to Staphylococcus aureus pathobiologyR01AI105129 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI TORRES, VICTOR J. · 2014 to 2023
$4.9M
Role of precipitous virulence in invasiveness of community-acquired methicillin-rR01AI103268 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, TORRES, VICTOR J. · 2013 to 2017
$2.1M
The molecular control of bacterial programmed cell deathR01AI125589 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAYLES, KENNETH W. · 2016 to 2020
$1.9M
Integrating Global Responses to Nutrient Limitation in Gram-positive BacteriaR00GM099893 · NIGMS · GEORGETOWN UNIVERSITY · PI BRINSMADE, SHAUN R · 2013 to 2015
$725k
Role of amino acids and GTP in Staphylococcus aureus pathogenesisR21AI123708 · NIAID · GEORGETOWN UNIVERSITY · PI BRINSMADE, SHAUN R · 2017 to 2018
$428k
Integrating Global Responses to Nutrient Limitation in Gram-positive BacteriaK99GM099893 · NIGMS · TUFTS UNIVERSITY BOSTON · PI BRINSMADE, SHAUN R · 2012 to 2012
$90k
NIAID NIH HHS P01 AI083211NIAID NIH HHS R01 AI099394NIAID NIH HHS R01 AI103268NIAID NIH HHS R01 AI105129NIAID NIH HHS R01 AI125589NIAID NIH HHS R21 AI123708NIAID NIH HHS T32 AI007180NIGMS NIH HHS K99 GM099893NIGMS NIH HHS R00 GM099893
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NutrientsBacterial ProteinsCells, CulturedCulture MediaGene Expression Regulation, BacterialHumansLeukocidinsNeutrophilsPromoter Regions, GeneticProtein KinasesRecombinant ProteinsRepressor ProteinsStaphylococcus aureusTranscription FactorsVirulenceVirulence FactorsBacterial ProteinsCodY protein, Staphylococcus aureusCulture MediaLeukocidinsNutrientsProtein KinasesRecombinant ProteinsRepressor ProteinsSaeR protein, Staphylococcus aureusSaeS protein, Staphylococcus aureusTranscription FactorsVirulence Factorsbranched-chain amino acidsCodYgene regulationSaeSae TCSStaphylococcus aureustwo-component systemvirulence

Identifiers

PMID29378891
PMCPMC5869476
OpenAlexW2789404724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.