Evidence map›Paper›PMID 29378883›Full record

ArticleJournal of bacteriology2018

Endopeptidase PepO Regulates the SpeB Cysteine Protease and Is Essential for the Virulence of Invasive M1T1 Streptococcus pyogenes.

Stephan Brouwer, Amanda J Cork, Cheryl-Lynn Y Ong, Timothy C Barnett, Nicholas P West, Kevin S McIver, Mark J Walker

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Virulence · 2020
    Article
  12. Article
  13. Novel Probiotic Mechanisms of the Oral BacteriumApplied and environmental microbiology · 2019
    Article
  14. Article
  15. ModelingFrontiers in cellular and infection microbiology · 2019
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Stephan Brouwer *Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia.
Amanda J Cork *Australian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia.
Cheryl-Lynn Y OngAustralian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia.
Timothy C BarnettAustralian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia.
Nicholas P WestAustralian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia.
Kevin S McIverDepartment of Cell Biology and Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA.ORCID https://orcid.org/0000-0002-4769-4463
Mark J WalkerAustralian Infectious Diseases Research Centre and School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Australia mark.walker@uq.edu.au.
The University of Queensland · AUUniversity of Maryland, College Park · US

Funding

PRD-Containing Virulence Regulators of Pathogenic StreptococciR01AI047928 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MCIVER, KEVIN S. · 2001 to 2023
$6.5M
NIAID NIH HHS R01 AI047928
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, BacterialAnimalsAnimals, Genetically ModifiedBacterial ProteinsCysteine EndopeptidasesDisease Models, AnimalExotoxinsGene Expression ProfilingHumansMiceMutagenesisNeutrophilsReverse Transcriptase Polymerase Chain ReactionStreptococcal InfectionsStreptococcus pyogenesVirulenceBacterial ProteinsCysteine Endopeptidaseserythrogenic toxinExotoxinsVirulence FactorsendopeptidasepathogenesisPepOSpeBStreptococcus pyogenesvirulence regulation

Identifiers

PMID29378883
PMCPMC5869480
OpenAlexW2785768254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.