ArticleThorax2018
High prevalence of latent tuberculosis and bloodborne virus infection in a homeless population.
Article in Thorax, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Barriers and facilitators to hepatitis C screening and treatment for people with lived experience of homelessness: A mixed-methods systematic review.Health expectations : an international journal of public participation in health care and health policy · 2022Pooled it
- Tuberculosis, vulnerabilities, and HIV in homeless persons: a systematic review.Revista de saude publica · 2022Pooled it
- Homelessness, unstable housing, and risk of HIV and hepatitis C virus acquisition among people who inject drugs: a systematic review and meta-analysis.The Lancet. Public health · 2021Pooled it
- Tuberculosis infection in an urban homeless population.Epidemiology and infection · 2026Article
- Demographic and Health Characteristics in Hispanic versus non-Hispanic Groups Experiencing Homelessness in New Mexico.Journal of racial and ethnic health disparities · 2026Article
- Diagnosis and management of tuberculosis infection in inclusion health populations in London.BMC infectious diseases · 2024Article
- Respiratory Syncytial Virus, Influenza and SARS-CoV-2 in Homeless People from Urban Shelters: A Systematic Review and Meta-Analysis (2023).Epidemiologia (Basel, Switzerland) · 2024Review
- Why were COVID-19 infections lower than expected amongst people who are homeless in London, UK in 2020? Exploring community perspectives and the multiple pathways of health inequalities in pandemics.SSM. Qualitative research in health · 2022Article
- "It's too hard" - the management of latent TB in under-served populations in the UK: a qualitative study.BMC health services research · 2022Article
- Nurse-led intervention to decrease drug use among LTBI positive homeless adults.Public health nursing (Boston, Mass.) · 2022Article
- Tuberculosis among People Living on the Street and Using Alcohol, Tobacco, and Illegal Drugs: Analysis of Territories in Extreme Vulnerability and Trends in Southern Brazil.International journal of environmental research and public health · 2022Article
- Drug resistantPeerJ · 2022Article
- Tuberculosis Surveillance in Romania Among Vulnerable Risk Groups Between 2015 and 2017.Therapeutics and clinical risk management · 2022Article
- Article
- Evaluation of Hepatitis C Test and Treat Interventions Targeted at Homeless Populations (Outside London) in England During the COVID-19 Pandemic.Clinical liver disease · 2021Article
- Treating latent tuberculosis infection (LTBI) with isoniazid and rifapentine (3HP) in an inner-city population with psychosocial barriers to treatment adherence: A qualitative descriptive study.PLOS global public health · 2021Article
- From peer-based to peer-led: redefining the role of peers across the hepatitis C care pathway: HepCare Europe.The Journal of antimicrobial chemotherapy · 2019Observational
- QuantiFERON-TB Gold Versus Tuberculin Screening and Care Retention Among Persons Experiencing Homelessness: Georgia, 2015-2017.American journal of public health · 2019Article
- Hepatitis B vaccination uptake in hard-to-reach populations in London: a cross-sectional study.BMC infectious diseases · 2019Article
- Seroprevalence of HCV, HBV and HIV in two inner-city London emergency departments.Epidemiology and infection · 2019Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 3 countries.
Funding
Abstract
introductionUrban homeless populations in the UK have been shown to have high rates of active tuberculosis, but less is known about the prevalence of latent tuberculosis infection (LTBI). This study aimed to estimate the prevalence of LTBI among individuals using homeless hostels in London.
methodsWe performed a cross-sectional survey with outcome follow-up in homeless hostels in London. Our primary outcome was prevalence of LTBI. Recruitment for the study took place between May 2011 and June 2013. To estimate an LTBI prevalence of 10% with 95% CIs between 8% and 13%, we required 500 participants.
results491/804 (61.1%) individuals agreed to be screened. The prevalence of LTBI was 16.5% (81/491; 95% CI 13.2 to 19.8). In UK-born individuals, a history of incarceration was associated with increased risk of LTBI (OR 3.49; 95% CI 1.10 to 11.04; P=0.018) after adjusting for age, length of time spent homeless and illicit drug use. Of the three subjects who met English treatment guidelines for LTBI at the time of the study, none engaged with services after referral for treatment. Prevalence of past hepatitis B infection was 10.4% (51/489; 95% CI 7.7 to 13.1), and 59.5% (291/489; 95% CI 55.1 to 63.9) of individuals were non-immune. Prevalence of current hepatitis C infection was 10.4% (51/489; 95% CI 7.8 to 13.1).
conclusionsThis study demonstrates the high prevalence of LTBI in homeless people in London and the associated poor engagement with care. There is a large unmet need for LTBI and hepatitis C infection treatment, and hepatitis B vaccination, in this group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.