Evidence map›Paper›PMID 29378853›Full record

ArticleHypertension (Dallas, Tex. : 1979)2018

Left Ventricular Hypertrophy and Remodeling and Risk of Cognitive Impairment and Dementia: MESA (Multi-Ethnic Study of Atherosclerosis).

Kasra Moazzami, Mohammad Reza Ostovaneh, Bharath Ambale Venkatesh, Mohammadali Habibi, Kihei Yoneyama, Colin Wu, Kiang Liu, Isabel Pimenta, Annette Fitzpatrick, Steven Shea and 6 more

Open access · bronzeAbstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  6. Left ventricular remodeling and diastolic dysfunction predict cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Kasra MoazzamiFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Mohammad Reza OstovanehFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Bharath Ambale VenkateshFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Mohammadali HabibiFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Kihei YoneyamaFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Colin WuFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Kiang LiuFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Isabel PimentaFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Annette FitzpatrickFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Steven SheaFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Robyn L McClellandFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Susan HeckbertFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Rebecca F GottesmanFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
David A BluemkeFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
Timothy M HughesFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.).
João A C LimaFrom the Department of Cardiology (K.M., M.R.O., B.A.V., M.H., K.Y., I.P., J.A.C.L.) and Department of Neurology (R.F.G.), Johns Hopkins University, Baltimore, MD; Department of Medicine, Rutgers New Jersey Medical School, State University of New Jersey, Newark (K.M.); Office of Biostatistics, National Heart, Lung, and Blood Institute, Bethesda, MD (C.W.); Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (K.L.); Department of Family Medicine, School of Medicine (A.F.), Department of Epidemiology, School of Medicine (A.F.), Department of Global Health, School of Public Health (A.F.), Department of Biostatistics (R.L.M.), and Department of Epidemiology (S.H.), University of Washington, Seattle; Department of Medicine, Columbia University College of Physicians and Surgeons, New York City, NY (S.S.); National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health Clinical Center, Bethesda, MD (D.A.B.); and Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC (T.M.H.). jlima@jhmi.edu.
Columbia University · USNational Institutes of Health Clinical Center · USRutgers New Jersey Medical SchoolRutgers, The State University of New Jersey · USNational Heart Lung and Blood Institute · USNational Institute of Biomedical Imaging and Bioengineering · US

Funding

Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Regional Dysfunction by MRI in Incident Heart FailureR01HL066075 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI LIMA, JOAO A C · 2001 to 2009
$4.0M
Cigarette Smoke and Susceptibility to Influenza InfectionR01HL095163 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JASPERS, ILONA, NOAH, TERRY L · 2009 to 2013
$2.0M
Adjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3M
Neuroepidemiology of the vascular contribution to cognitive impairment and Alzheimer's diseaseK24AG052573 · NIA · JOHNS HOPKINS UNIVERSITY · PI GOTTESMAN, REBECCA F · 2016 to 2020
$803k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095161 · HC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN · 1999 to 2001
$642k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095165 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1999 to 2001
$616k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095160 · HC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SAAD, MOHAMMED F · 1999 to 2001
$592k
SUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095164 · HC · NORTHWESTERN UNIVERSITY · PI LIU, KIANG JOHN · 1999 to 2001
$511k
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL066075NIA NIH HHS K24 AG052573
6 · The paper itself

Abstract

Limited information exists on the longitudinal association between the left ventricular (LV) structure and function and future cognitive impairment and dementia in a large population without clinically recognized cardiovascular disease at baseline. The aim of the present study was to investigate the association between cardiac structure and function and risk of dementia and cognitive impairment in the MESA (Multi-Ethnic Study of Atherosclerosis) cohort. Measures of LV structure and function were determined using magnetic resonance imaging at baseline in 4999 participants free of clinically diagnosed cardiovascular disease and dementia. Probable incident clinical dementia was ascertained from hospitalization discharge records. Cognitive function was evaluated using tests addressing global cognitive function, processing speed, and memory. Associations of measures of LV structure and function with the incidence of clinically diagnosed dementia and cognitive performance were evaluated using Cox proportional hazard regression models adjusted for demographics, cardiovascular risk factors, and cardiovascular events. During a median follow-up of 12 years, 130 probable incident dementia cases were documented. Higher LV mass index (hazard ratio, 1.01; 95% confidence interval, 1.00-1.02) and LV mass-to-volume ratio (hazard ratio, 2.37; 95% confidence interval, 1.25-4.43) were independently associated with incident dementia and impaired cognitive function. Measures of LV function were not associated with risk of dementia or cognitive impairment. In conclusion, in a multiethnic cohort of participants without clinically detected cardiovascular disease and dementia at baseline, LV hypertrophy and concentric remodeling were independently associated with incident dementia and cognitive impairment.

Indexed as

AgedAged, 80 and overAge DistributionCognitive DysfunctionCohort StudiesDatabases, FactualDementiaEthnicityFemaleFollow-Up StudiesHumansHypertrophy, Left VentricularIncidenceMagnetic Resonance Imaging, CineMaleMiddle Agedcognitive dysfunctiondementiafollow-up studiesheart ventriclesrisk factors

Identifiers

PMID29378853
PMCPMC5812794
OpenAlexW2792524763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.