Evidence map›Paper›PMID 29378810›Full record

ReviewGenetics2018

Repressive Chromatin in

Julie Ahringer, Susan M Gasser

Open access · bronzeAbstract readReview
In one paragraph

Review in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
5.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
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  4. Epigenetic constraints and enhancer innovation link neuronal plasticity to evolutionary adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  7. Review
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  16. Review
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Julie AhringerThe Gurdon Institute, University of Cambridge CB2 1QN, United Kingdom j.ahringer@gurdon.cam.ac.uk susan.gasser@fmi.ch.ORCID 0000-0002-7074-4051
Susan M GasserFriedrich Miescher Institute for Biomedical Research (FMI), 4058 Basel, Switzerland, and j.ahringer@gurdon.cam.ac.uk susan.gasser@fmi.ch.ORCID 0000-0003-3610-9123
University of Basel · CHUniversity of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Chromatin is organized and compacted in the nucleus through the association of histones and other proteins, which together control genomic activity. Two broad types of chromatin can be distinguished: euchromatin, which is generally transcriptionally active, and heterochromatin, which is repressed. Here we examine the current state of our understanding of repressed chromatin in

Indexed as

AnimalsCaenorhabditis elegansCellular ReprogrammingChromatinGene Expression RegulationGenomeHeterochromatinHistone CodeHistone-Lysine N-MethyltransferaseHistonesLoss of Function MutationMethylationNuclear LaminaPhenotypeRepetitive Sequences, Nucleic AcidRNA InterferenceChromatinHeterochromatinHistone-Lysine N-MethyltransferaseHistonesC. eleganschromatinH3K27meH3K9meheterochromatinhistone methylationWormBook

Identifiers

PMID29378810
PMCPMC5788517
OpenAlexW2786896132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.