Evidence map›Paper›PMID 29378596›Full record

ReviewJournal of translational medicine2018

Myeloid-derived suppressor cells in transplantation: the dawn of cell therapy.

Weitao Zhang, Jiawei Li, Guisheng Qi, Guowei Tu, Cheng Yang, Ming Xu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 68 citations in OpenAlex.

  1. LDLRJournal of clinical and translational hepatology · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  7. Chimerism-Mediated Tolerance in Intestinal Transplantation.Gastroenterology clinics of North America · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. A Lesson of Immunosuppression in Renal Transplant: Retreat or Hold?The Yale journal of biology and medicine · 2023
    Observational
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weitao ZhangDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, 180 Fenglin Road, Shanghai, 200032, China.
Jiawei LiDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, 180 Fenglin Road, Shanghai, 200032, China.
Guisheng QiDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, 180 Fenglin Road, Shanghai, 200032, China.
Guowei TuDepartment of Intensive Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Cheng YangDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, 180 Fenglin Road, Shanghai, 200032, China. esuperyc@163.com.ORCID 0000-0003-4060-2746
Ming XuDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai Key Laboratory of Organ Transplantation, 180 Fenglin Road, Shanghai, 200032, China. xu.ming@zs-hospital.sh.cn.
Fudan University · CN

Funding

National Natural Science Foundation of China 81370852National Natural Science Foundation of China 81400752National Natural Science Foundation of China 81500067National Natural Science Foundation of China 81500570National Natural Science Foundation of China 81770746
6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) are a series of innate cells that play a significant role in inhibiting T cell-related responses. This heterogeneous population of immature cells is involved in tumor immunity. Recently, the function and importance of MDSCs in transplantation have garnered the attention of scientists and have become an important focus of transplantation immunology research because MDSCs play a key role in establishing immune tolerance in transplantation. In this review, we summarize recent studies of MDSCs in different types of transplantation. We also focus on the influence of immunosuppressive drugs on MDSCs as well as future obstacles and research directions in this field.

Indexed as

Cell- and Tissue-Based TherapyAnimalsHumansImmune ToleranceImmunosuppressive AgentsMyeloid-Derived Suppressor CellsTransplantationImmunosuppressive AgentsCell therapyImmunologyMyeloid-derived suppressor cell (MDSC)RegulationTransplantation

Identifiers

PMID29378596
PMCPMC5789705
OpenAlexW2789180158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.