Evidence map›Paper›PMID 29378548›Full record

ArticleBMC public health2018

"I beg you…breastfeed the baby, things changed": infant feeding experiences among Ugandan mothers living with HIV in the context of evolving guidelines to prevent postnatal transmission.

Emma Dunkley, Scholastic Ashaba, Bridget Burns, Kasey O'Neil, Naomi Sanyu, Cecilia Akatukwasa, Jasmine Kastner, Nicole S Berry, Christina Psaros, Lynn T Matthews and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Emma DunkleyFaculty of Health Sciences, Simon Fraser University, Blusson Hall Rm 10522, 8888 University Drive, Burnaby, B.C. V5A 1S6, Canada.
Scholastic AshabaMbarara University of Science and Technology (MUST), Mbarara, Uganda.
Bridget BurnsMassachusetts General Hospital (MGH) Global Health, Boston, MA, USA.
Kasey O'NeilMassachusetts General Hospital (MGH) Global Health, Boston, MA, USA.
Naomi SanyuMbarara University of Science and Technology (MUST), Mbarara, Uganda.
Cecilia AkatukwasaMbarara University of Science and Technology (MUST), Mbarara, Uganda.
Jasmine KastnerFaculty of Health Sciences, Simon Fraser University, Blusson Hall Rm 10522, 8888 University Drive, Burnaby, B.C. V5A 1S6, Canada.
Nicole S BerryFaculty of Health Sciences, Simon Fraser University, Blusson Hall Rm 10522, 8888 University Drive, Burnaby, B.C. V5A 1S6, Canada.
Christina PsarosBehavioral Medicine, Department of Psychiatry, Massachusetts General Hospital (MGH), Boston, MA, USA.
Lynn T MatthewsMassachusetts General Hospital (MGH) Global Health, Boston, MA, USA.
Angela KaidaFaculty of Health Sciences, Simon Fraser University, Blusson Hall Rm 10522, 8888 University Drive, Burnaby, B.C. V5A 1S6, Canada. kangela@sfu.ca.
Simon Fraser University · CAMbarara University of Science and Technology · UGMGH Institute of Health Professions · USMassachusetts General Hospital · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 1988 to 2026
$93.6M
TB PREVENTION AND HIV IN THE HOMELESS--AN INTERVENTIONR01MH054907 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BANGSBERG, DAVID ROY · 1995 to 2014
$20.7M
Periconception HIV risk reduction for HIV-discordant couples in UgandaK23MH095655 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MATTHEWS, LYNN T · 2011 to 2015
$854k
Mentoring Patient Oriented Adherence Research in UgandaK24MH087227 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BANGSBERG, DAVID ROY · 2009 to 2013
$776k
Fertility desire and pregnancy in a cohort of discordant Ugandan couples on ARTR21HD069194 · NICHD · SIMON FRASER UNIVERSITY · PI KAIDA, ANGELA KANANA · 2011 to 2012
$303k
NIAID NIH HHS P30 AI027763NICHD NIH HHS R21 HD069194NIMH NIH HHS K23 MH095655NIMH NIH HHS K23-MH095655NIMH NIH HHS K24 MH087227NIMH NIH HHS K24-MH87227NIMH NIH HHS R01 MH054907NIMH NIH HHS R01-MH54907
6 · The paper itself

Abstract

backgroundFor women living with HIV (WLWH) in low- and middle-income countries, World Health Organization (WHO) infant feeding guidelines now recommend exclusive breastfeeding until six months followed by mixed feeding until 24 months, alongside lifelong maternal antiretroviral therapy (ART). These recommendations represent the sixth major revision to WHO infant feeding guidelines since 1992. We explored how WLWH in rural Uganda make infant feeding decisions in light of evolving recommendations.

methodsWe conducted semi-structured interviews with 20 postpartum Ugandan WLWH accessing ART, who reported pregnancy < 2 years prior to recruitment. Interviews were conducted between February-August 2014 with babies born between March 2012-October 2013, over which time, the regional HIV treatment clinic recommended lifelong ART for all pregnant and breastfeeding women (Option B+). Content analysis was used to identify major themes. Infant feeding experiences was an emergent theme. NVivo 10 software was used to organize analyses.

resultsAmong 20 women, median age was 33 years [IQR: 28-35], number of livebirths was 3 [IQR: 2-5], years on ART was 2.3 [IQR: 1.5-5.1], and 95% were virally suppressed. Data revealed that women valued opportunities to reduce postnatal transmission. However, women made infant feeding choices that differed from recommendations due to: (1) perception of conflicting recommendations regarding infant feeding; (2) fear of prolonged infant HIV exposure through breastfeeding; and (3) social and structural constraints shaping infant feeding decision-making.

conclusionsWLWH face layered challenges navigating evolving infant feeding recommendations. Further research is needed to examine guidance and decision-making on infant feeding choices to improve postpartum experiences and outcomes. Improved communication about changes to recommendations is needed for WLWH, their partners, community members, and healthcare providers.

Indexed as

Guidelines as TopicInfant Nutritional Physiological PhenomenaAdultAnti-Retroviral AgentsBreast FeedingChoice BehaviorFearFeeding BehaviorFemaleHIV InfectionsHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalMothersRural PopulationAnti-Retroviral AgentsBreastfeedingHIVHIV-positive womenInfant nutritionOption B+Perinatal transmissionPostnatal transmissionWomen

Identifiers

PMID29378548
PMCPMC5789624
OpenAlexW2795579092

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.