Evidence map›Paper›PMID 29378474›Full record

ArticleThyroid : official journal of the American Thyroid Association2018

Circulating BRAF

Carrie C Lubitz, Tiannan Zhan, Viswanath Gunda, Salma Amin, Benjamin J Gigliotti, Abbey L Fingeret, Tammy M Holm, Heather Wachtel, Peter M Sadow, Lori J Wirth and 3 more

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. 2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.Thyroid : official journal of the American Thyroid Association · 2021
    Guideline
  2. Article
  3. Review
  4. Review
  5. Detection of theJournal of clinical medicine · 2024
    Review
  6. Opportunities and Challenges of Liquid Biopsy in Thyroid Cancer.International journal of molecular sciences · 2021
    Review
  7. Molecular-Driven Therapy in Advanced Thyroid Cancer.Current treatment options in oncology · 2021
    Review
  8. Detection of Circulating Tumor DNA in Patients with Thyroid Nodules.International journal of endocrinology · 2021
    Article
  9. Article
  10. Medical professor as a patient.Korean journal of medical education · 2020
    Article
  11. Article
  12. Review
  13. CirculatingJCO precision oncology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Carrie C Lubitz1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Tiannan Zhan2 Institute for Technology Assessment, Massachusetts General Hospital , Boston, Massachusetts.
Viswanath Gunda1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Salma Amin1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Benjamin J Gigliotti3 Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts.
Abbey L Fingeret1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Tammy M Holm1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Heather Wachtel1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Peter M Sadow4 Department of Pathology, Massachusetts General Hospital , Boston, Massachusetts.
Lori J Wirth3 Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts.
Ryan J Sullivan3 Department of Medicine, Massachusetts General Hospital , Boston, Massachusetts.
David J Panka5 Department of Medicine, Beth Israel Deaconess Medical Center , Boston, Massachusetts.
Sareh Parangi1 Department of Surgery, Massachusetts General Hospital , Boston, Massachusetts.
Massachusetts General Hospital · USBeth Israel Deaconess Medical Center · US

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
The Role of BRAF Mutation in Thyroid Cancer InvasionR01CA149738 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARANGI, SAREH · 2011 to 2015
$1.6M
Optimization of Treatment of Papillary Thyroid Cancer: A Risk-tailored ApproachK07CA177900 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CUNNINGHAM, CARRIE ELIZABETH · 2014 to 2018
$712k
NCI NIH HHS K07 CA177900NCI NIH HHS R01 CA149738NIDDK NIH HHS T32 DK007028
6 · The paper itself

Abstract

backgroundBRAF

methodsCirculating BRAF

resultsIn a murine model of anaplastic thyroid carcinoma with BRAF

conclusionsThis study shows the correlation of blood BRAF

Indexed as

MutationAdultAgedAnimalsDisease Models, AnimalFemaleHumansMaleMiceMiddle AgedProto-Oncogene Proteins B-rafThyroid Carcinoma, AnaplasticThyroidectomyThyroid NeoplasmsBRAF protein, humanProto-Oncogene Proteins B-rafbiomarkerBRAFV600Ecirculation tumor cellspapillary thyroid cancerthyroid cancer

Identifiers

PMID29378474
PMCPMC5865613
OpenAlexW2787288868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.